Bioteknologian ja molekulaarisen lääketieteen laitos
Department of Biotechnology and Molecular Medicine

Julkaisut 2009
Publications 2009

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1 Airenne KJ. Optimization of baculovirus-mediated gene delivery into vertebrate cells.
2 Airenne KJ et al. Baculovirus-mediated gene transfer: An emerging universal concept.
3 Alhonen L et al. Transgenic animals modelling polyamine metabolism-related diseases.
4 Anisimov A et al. Activated forms of VEGF-C and VEGF-D provide improved vascular function in skeletal muscle.
5 Eeva J et al. Feedback regulation of mitochondria by caspase-9 in the B cell receptor-mediated apoptosis.
6 Haukkala J et al. (68)Ga-DOTA-RGD peptide: biodistribution and binding into atherosclerotic plaques in mice.
7 Hedman M et al. Eight-year safety follow-up of coronary artery disease patients after local intracoronary VEGF gene transfer.
8 Heinonen M. Apelin, Orexin A and Ghrelin Levels in Obesity and the Metabolic Syndrome.
9 Hyvönen MT et al. Divergent regulation of the key enzymes of polyamine metabolism by chiral alpha-methylated polyamine analogues.
10 Häkkinen MR et al. Synthesis of novel deuterium labelled derivates of N-alkylated polyamines.
11 Jin HT et al. Changes in blood polyamine levels in human acute pancreatitis.
12 Juntunen R et al. Suboptimal recognition of a T cell epitope of the major dog allergen Can f 1 by human T cells.
13 Kaikkonen MU et al. (Strept)avidin-displaying lentiviruses as versatile tools for targeting and dual imaging of gene delivery.
14 Kangasniemi L et al. Extended release of adenovirus from silica implants in vitro and in vivo.
15 Kanninen K et al. Intrahippocampal injection of a lentiviral vector expressing Nrf2 improves spatial learning in a mouse model of Alzheimer's disease.
16 Kansanen E et al. Nrf2-dependent and -independent responses to nitro-fatty acids in human endothelial cells: identification of heat shock response as the major pathway activated by nitro-oleic acid.
17 Kansanen E et al. Regulation of Nrf2-dependent gene expression by 15-deoxy-Delta12,14-prostaglandin J2.
18 Karvinen H et al. PDGF-C and -D and their receptors PDGFR-alpha and PDGFR-beta in atherosclerotic human arteries.
19 Keinänen R et al., ed. The Third Annual Post-Graduate Symposium of the Graduate School of Molecular Medicine. Winter School 2009 Abstracts.
20 Ketola A. Gene and Virotherapy Against Osteosarcoma .
21 Khomutov AR et al. Methylated analogs of spermine and spermidine as tools to investigate cellular functions of polyamines and the enzymes of their metabolism.
22 Kinnunen K. Vascular Endothelial Growth Factors in Eye Diseases. Pathophysiology and New Therapeutic Strategies for Retinal and Choroideal Angiogenesis.
23 Kinnunen K et al. Baculovirus is an efficient vector for the transduction of the eye: comparison of baculovirus- and adenovirus-mediated intravitreal vascular endothelial growth factor D gene transfer in the rabbit eye.
24 Kinnunen K et al. Differences in retinal neovascular tissue and vitreous humour in patients with type 1 and type 2 diabetes.
25 Koivumäki JT et al. Regulation of excitation-contraction coupling in mouse cardiac myocytes: integrative analysis with mathematical modelling.
26 Korhonen T et al. Model of excitation-contraction coupling of rat neonatal ventricular myocytes.
27 Korpisalo-Pirinen P. Angiogenic Gene Therapy. Vascular Endothelial Growth Factors and Platelet Derived Growth Factors in Vascular Growth and Stabilization.
28 Kärkkäinen A-M et al. Vascular endothelial growth factor-D transgenic mice show enhanced blood capillary density, improved postischemic muscle regeneration, and increased susceptibility to tumor formation.
29 Kärkkäinen H-R et al. A 96-well format for a high-throughput baculovirus generation, fast titering and recombinant protein production in insect and mammalian cells.
30 Laakkonen JP et al. Clathrin-independent entry of baculovirus triggers uptake of E. coli in non-phagocytic human cells.
31 Lahtinen L et al. Expression of urokinase-type plasminogen activator receptor is increased during epileptogenesis in the rat hippocampus.
32 Laitinen I et al. Uptake of inflammatory cell marker [(11)C]PK11195 into mouse atherosclerotic plaques.
33 Laitinen I et al. Evaluation of alphavbeta3 integrin-targeted positron emission tomography tracer 18F-galacto-RGD for imaging of vascular inflammation in atherosclerotic mice.
34 Langford G et al. A preclinical assessment of the safety and biodistribution of an adenoviral vector containing the herpes simplex virus thymidine kinase gene (Cerepro(R)) after intracerebral administration.
35 Lesch H. Lentiviral Vectors for Gene Therapy Based on Avidin Fusion Proteins. Targeting, Imaging and Baculovirus Mediated New Method for Lentivirus Production .
36 Lesch HP et al. Avidin fusion protein-expressing lentiviral vector for targeted drug delivery.
37 Loboda A et al. HIF-1 induction attenuates Nrf2-dependent IL-8 expression in human endothelial cells.
38 Lähteenvuo J. Gene Therapy for Ischemic Diseases - WEGFs in Myocardial and Peripheral Ischemia.
39 Lähteenvuo JE et al. Vascular endothelial growth factor-B induces myocardium-specific angiogenesis and arteriogenesis via vascular endothelial growth factor receptor-1- and neuropilin receptor-1-dependent mechanisms.
40 Määttä AM et al. Adenovirus mediated herpes simplex virus-thymidine kinase/ganciclovir gene therapy for resectable malignant glioma.
41 Norrmén C et al. FOXC2 controls formation and maturation of lymphatic collecting vessels through cooperation with NFATc1.
42 Nuutinen U et al. PDTC enables type I TRAIL signaling in type II follicular lymphoma cells.
43 Pirinen E. Involvement of Polyamine Catabolism in the Regulation of Glucose, Energy and Cholesterol Metabolism in Mice.
44 Roy H et al. Molecular genetics of atherosclerosis.
45 Sallinen H et al. Antiangiogenic gene therapy with soluble VEGFR-1, -2 and -3 reduces the growth of solid human ovarian carcinoma in mice.
46 Samaranayake H et al. Challenges in monoclonal antibody-based therapies.
47 Savolainen E et al. Prevalence of antibodies against Chlamydia trachomatis and incidence of C. trachomatis-induced reactive arthritis in an early arthritis series in Finland in 2000.
48 Scaldaferri F et al. VEGF-A links angiogenesis and inflammation in inflammatory bowel disease pathogenesis.
49 Toivanen PI et al. Novel vascular endothelial growth factor D variants with increased biological activity.
50 Turunen MP et al. Epigenetics and atherosclerosis.
51 Turunen MP et al. Efficient regulation of VEGF expression by promoter-targeted lentiviral shRNAs based on epigenetic mechanism: a novel example of epigenetherapy.
52 Uimari A et al. Spermine analogue-regulated expression of spermidine/spermine N1-acetyltransferase and its effects on depletion of intracellular polyamine pools in mouse fetal fibroblasts.
53 Vajanto I et al. Antegrade flow and peripheral resistance determine the level of endogenous arteriogenesis in patients with superficial femoral artery occlusion.
54 Viita H. 15-Lipoxygenase-1 in Atherosclerosis, Angiogenesis and Tumorigenesis. Studies with Retro- and Adenovirus Mediated Gene Transfer Techniques.
55 Viita H et al. Intravitreal adenoviral 15-lipoxygenase- 1 gene transfer prevents vascular endothelial growth factor A-induced neovascularization in rabbit eyes.
56 Wirth T et al. Clinical trials for glioblastoma multiforme using adenoviral vectors.
57 Ylä-Herttuala S. Gene therapy with vascular endothelial growth factors.
58 Ylä-Herttuala S. Geenihoito.
59 Zahedi K et al. Spermidine/spermine-N1-acetyltransferase ablation protects against liver and kidney ischemia-reperfusion injury in mice.
60 Zhang F et al. VEGF-B is dispensable for blood vessel growth but critical for their survival, and VEGF-B targeting inhibits pathological angiogenesis.

Bioteknologian ja molekulaarisen lääketieteen laitos Department of Biotechnology and Molecular Medicine
Julkaisutietokanta 27.5.2010 Publications Data Base 27.5.2010