Farmakologian ja toksikologian laitos
Department of Pharmacology and Toxicology

Julkaisut 2007 (alustava)
Publications 2007 (preliminary)

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1 Biggs JS et al. Transcription factor binding to a putative double E-box motif represses CYP3A4 expression in human lung cells.
2 Bremer S et al. In vitro tests for detecting chemicals affecting the embryo implantation process. The report and recommendations of ECVAM workshop 62 - A strategic workshop of the EU ReProTect project.
3 Elovaara E et al. Polycyclic aromatic hydrocarbon (PAH) metabolizing enzyme activities in human lung, and their inducibility by exposure to naphthalene, phenanthrene, pyrene, chrysene, and benzo(a)pyrene as shown in the rat lung and liver.
4 Garcia-Horsman JA et al. Deficient activity of mammalian prolyl oligopeptidase on the immunoactive peptide digestion in coeliac disease.
5 Garcķa-Horsman JA et al. On the role of prolyl oligopeptidase in health and disease.
6 Gratz S et al. Lactobacillus rhamnosus strain GG reduces aflatoxin B1 transport, metabolism, and toxicity in Caco-2 cells.
7 Huttunen KM et al. Novel cyclic phosphate prodrug approach for cytochrome P450-activated drugs containing an alcohol functionality.
8 Jalkanen AJ et al. Beneficial effect of prolyl oligopeptidase inhibition on spatial memory in young but not in old scopolamine-treated rats.
9 Jarho EM et al. 2(S)-(cycloalk-1-enecarbonyl)-1-(4-phenyl-butanoyl)pyrrolidines and 2(S)-(aroyl)-1-(4-phenylbutanoyl)pyrrolidines as prolyl oligopeptidase inhibitors.
10 Kaabachi O et al. Clonidine 1 µg/kg is a safe and effective adjuvant to plain bupivacaine in spinal anesthesia in adolescents.
11 Kemppainen TP et al. Pain treatment and recovery after endoscopic sinus surgery.
12 Korhonen LE et al. New potent and selective cytochrome P450 2B6 (CYP2B6) inhibitors based on three-dimensional quantitative structure-activity relationship (3D-QSAR) analysis.
13 Kumpulainen E et al. Paracetamol (Acetaminophen) penetrates readily into the cerebrospinal fluid of children after intravenous administration.
14 Kääriäinen TM et al. Comparison of the effects of deramciclane, ritanserin and buspirone on extracellular dopamine and its metabolites in striatum and nucleus accumbens of freely moving rats.
15 Laitinen K. Onko kannabiksesta lääkkeeksi?
16 Lampela P et al. Adverse drug effects in elderly people - a disparity between clinical examination and adverse effects self-reported by the patient.
17 Lampela P et al. Reply to letter by Foster, van der Molen and de Jong-van den Berg.
18 Loponen J et al. Prolamin hydrolysis in wheat sourdoughs with differing proteolytic activities.
19 Louhelainen M et al. Effects of levosimendan on cardiac remodeling and cardiomyocyte apoptosis in hypertensive Dahl/Rapp rats.
20 MacDonald E, Saarti J. Learning from other“s mistakes - one approach to teaching information literacy.
21 Mannila A et al. Plasma and cerebrospinal fluid concentrations of indomethacin in children after intravenous administration.
22 Mensio S et al. Lääkkeiden kliinisesti merkittävät yhteisvaikutukset sairaalassa.
23 Merlo DF et al. Ethics in studies on children and environmental health.
24 Mervaala E. Ravitsemus ja verenpaine.
25 Myllynen P et al. DNA damage caused by benzo(a)pyrene in MCF-7 cells is increased by verapamil probenecid and PSC833.
26 Myllynen P et al. The fate and effects of xenobiotics in human placenta.
27 Myöhänen TT et al. Distribution of immunoreactive prolyl oligopeptidase in human and rat brain.
28 Männistö PT et al. Prolyl oligopeptidase: A potential target for the treatment of cognitive disorders.
29 Mönkkönen KS et al. Hormonal regulation of G-alpha-i2 and mPR-alpha in immortalized human oviductal cell line OE-E6/E7.
30 Mönkkönen KS et al. Localization and variable expression of G{alpha}i2 in human endometrium and Fallopian tubes.
31 Mönkkönen KS et al. Intracerebroventricular antisense knockdown of G-alpha-i2 results in ciliary stasis and ventricular dilatation in the rat.
32 Palomäki VAB et al. Visualization of 2-arachidonoylglycerol accumulation and cannabinoid CB1 receptor activity in rat brain cryosections by functional autoradiography.
33 Peltonen J et al. Is there a role for PCR-SSCP among the methods for missense mutation detection of TP53 gene?
34 Penttinen P et al. DNA damage and p53 in RAW264.7 cells induced by the spores of co-cultivated Streptomyces californicus and Stachybotrys chartarum.
35 Pilvi TK et al. High-calcium diet with whey protein attenuates body-weight gain in high-fat-fed C57BI/6J mice.
36 Raunio H. Uskaltaako uuselintarvikkeita syödä.
37 Saarti J, MacDonald E. Luentosalin synkkyyden lieventäminen: farmakologisten faktojen opettaminen lääketieteen opiskelijoille musiikin avulla.
38 Soppi V et al. Early-phase pharmacokinetics of enteral and parenteral nimodipine in patients with acute subarachnoid haemorrhage - a pilot study.
39 Storvik M et al. Amygdala serotonin transporters in alcoholics measured by whole hemisphere autoradiography.
40 Turpeinen M et al. Predictive value of animal models for human cytochrome P450 (CYP)-mediated metabolism: A comparative study in vitro.
41 Valtola A et al. Does coronary artery bypass surgery affect metoprolol bioavailability.
42 Veijola M et al. Mitä asioita PKV-lääkkeistä ja huumausaineita sisältävistä lääkkeistä kysytään Kuopion Lääkeinformaatiokeskuksesta.
43 Vinogradova LV et al. Histaminergic modulation of acoustically induced running behavior in rats .
44 Vähäkangas K, Tuomisto J. Torjunta-aineet. Orgaaniset ympäristömyrkyt.
45 Warnakulasuriya S et al. Demonstration of ethanol-induced protein adducts in oral leukoplakia (pre-cancer) and cancer. 2008!!
46 Yavich L et al. Site-specific role of catechol-O-methyltransferase in dopamine overflow within prefrontal cortex and dorsal striatum.

Farmakologian ja toksikologian laitos Department of Pharmacology and Toxicology
Julkaisutietokanta 16.4.2008 Publications Data Base 16.4.2008