Bioteknologian ja molekulaarisen lääketieteen laitos
Department of Biotechnology and Molecular Medicine

Julkaisut 2005
Publications 2005

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1 Babu M et al. Effect of total colectomy and PYY infusion on food intake and body weight in rats.
2 Baluk P et al. Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation.
3 Bhardwaj S. Adenovirus Mediated Growth Factor Gene Transfer to Periadventitial Space. Effects on angiogenesis and intimal hyperplasia.
4 Bhardwaj S et al. VEGF-A, VEGF-D and VEGF-D(DeltaNDeltaC) induced intimal hyperplasia in carotid arteries.
5 Bhardwaj S et al. Periadventitial angiopoietin-1 gene transfer induces angiogenesis in rabbit carotid arteries.
6 Chaudhuri JD et al. Localization of M2 muscarinic receptor protein in parvalbumin and calretinin containing cells of the adult rat entorhinal cortex using two complementary methods.
7 Christensen R et al. Characterization of transgenic mice with the expression of phenylalanine hydroxylase and GTP cyclohydrolase I in the skin.
8 Dworakowska D et al. Clinical significance of apoptotic index in non-small cell lung cancer: correlation with p53, mdm2, pRb and p21(WAF1/CIP1) protein expression.
9 Erkkilä AT et al. Antibodies against oxidized LDL and cardiolipin and mortality in patients with coronary heart disease.
10 Grigorenko NA et al. New syntheses of alfa-methyl- and alfa,alfa'-dimethylspermine.
11 Grigorenko NA et al. Synthesis of (R)- and (S)-isomers of 1-methylspermidine.
12 Hakkarainen T. Enhancement of Cancer Gene Therapy With Modified Viral Vectors and Fusion Genes.
13 Hakkarainen T et al. VP22 does not significantly enhance enzyme prodrug cancer gene therapy as a part of a VP22-HSVTk-GFP triple fusion construct.
14 He Y et al. Vascular endothelial cell growth factor receptor 3-mediated activation of lymphatic endothelium is crucial for tumor cell entry and spread via lymphatic vessels.
15 Heikkilä A et al. Tumor suppressor and growth regulatory genes are overexpressed in severe early-onset preeclampsia - an array study on casespecific human preeclamptic placental tissue.
16 Heinonen MV et al. Apelin, orexin-A and leptin plasma levels in morbid obesity and effect of gastric banding.
17 Herzig K-H et al. Acute pancreatitis induced by activation of the polyamine catabolism in gene-modified mice and rats overexpressing spermidine/spermine N1-acetyltransferase.
18 Hytönen VP et al. Design and construction of highly stable, protease-resistant chimeric avidins.
19 Hytönen VP et al. Dual-affinity avidin molecules.
20 Jänne J. Tieteellisen kirjoittamisen opas. Julkaisun ja apurahahakemuksen laatiminen biotieteissä.
21 Jänne J. A Guide to Scientific Writing. Preparing an Article and a Grant Proposal in the Biosciences.
22 Jänne J et al. Animal disease models generated by genetic engineering of polyamine metabolism.
23 Järvinen A. Alpha-Methylated Polyamine Analoques. Tools to Study Polyamine Metabolism and Polyamine Oxidase.
24 Järvinen A et al. Metabolic stability of alfa-methylated polyamine derivatives and their use as substitutes for the natural polyamines.
25 Kanerva A et al. Noninvasive dual modality in vivo monitoring of the persistence and potency of a tumor targeted conditionally replicating adenovirus.
26 Katsube K et al. Vascular endothelial growth factor (VEGF) gene transfer enhances surgical revascularization of necrotic bone.
27 Ketola A et al. Properties of Sindbis virus vectors produced with a chimeric split helper system.
28 Khomutov AR et al. New oxaanalogues of spermine.
29 Kiehne K et al. Oesophageal defensin expression during Candida infection and reflux disease.
30 Koponen JK, Ylä-Herttuala S. Miten saada sydänlihasarpi sykkimään?
31 Krebs R et al. Dual role of vascular endothelial growth factor in experimental obliterative bronchiolitis.
32 Laitinen OH et al. A multipurpose vector system for the screening of libraries in bacteria, insect and mammalian cells and expression in vivo.
33 Laitinen OH et al. Avidin fusion protein strategies in targeted drug and gene delivery.
34 Leppänen P et al. Gene transfers of vascular endothelial growth factor-A, vascular endothelial growth factor-B, vascular endothelial growth factor-C, and vascular endothelial growth factor-D have no effects on atherosclerosis in hypercholesterolemic...
35 Luoma JS et al. Autoantibodies against oxidized LDL are associated with severe chest pain attacks in patients with coronary heart disease.
36 Markkanen JE et al. Growth factor-induced therapeutic angiogenesis and arteriogenesis in the heart - gene therapy.
37 Meriläinen O et al. HIV-1 TAT protein transduction domain mediates enhancement of enzyme prodrug cancer gene therapy in vitro: A study with TAT-TK-GFP triple fusion construct.
38 Niskanen EA et al. Chicken genome analysis reveals novel genes encoding biotin-binding proteins related to avidin family.
39 Nordlund HR et al. Tetravalent single-chain avidin: from subunits to protein domains via circularly permuted avidins.
40 Nordlund HR et al. Novel avidin-like protein from a root nodule symbiotic bacterium, Bradyrhizobium japonicum.
41 Nordlund HR et al. Production of Hev b5 as a fluorescent biotin-binding tripartite fusion protein in insect cells.
42 Otte J-M et al. Expression of keratinocyte growth factor and its receptor in adaptive changes of ileorectal pouch mucosa.
43 Pajusola K et al. Stabilized HIF-1alpha is superior to VEGF for angiogenesis in skeletal muscle via adeno-associated virus gene transfer.
44 Peräkylä M et al. Gene regulatory potential of nonsteroidal vitamin D receptor ligands.
45 Pietilä M et al. Disturbed keratinocyte differentiation in transgenic mice and organotypic keratinocyte cultures as a result of spermidine/spermine N1-acetyltransferase overexpression.
46 Puhakka H. Gene Therapy for Vascular Tickening.
47 Puhakka HL et al. Effects of vaccinia virus anti-inflammatory protein 35K and TIMP-1 gene transfers on vein graft stenosis in rabbits.
48 Puhakka HL et al. Tissue inhibitor of metalloproteinase 1 adenoviral gene therapy alone is equally effective in reducing restenosis as combination gene therapy in a rabbit restenosis model.
49 Pulkkanen KJ, Ylä-Herttuala S. Gene therapy for malignant glioma: current clinical status .
50 Päivärinta M. Phosphatidylinositol 3-Kinase and Type 2 Diabetes. Catalytic subunit p110beta as a can gene for type 2 diabetes and in vitro modelling of the insulin signalling pathway.
51 Radke PW et al. Vascular oligonucleotide transfer facilitated by a polymer-coated stent.
52 Rissanen TT et al. Blood flow remodels growing vasculature during vascular endothelial growth factor gene therapy and determines between capillary arterialization and sprouting angiogenesis.
53 Rossi J et al. Parasympathetic innervation and function of endocrine pancreas requires the glial cell line-derived factor familty receptor alpha2 (GFRalpha2).
54 Roy H et al. Adenovirus-mediated gene transfer of placental growth factor to perivascular tissue induces angiogenesis via upregulation of the expression of endogenous vascular endothelial growth factor-A.
55 Ruponen M et al. Nonviral gene delivery methods in cardiovascular diseases.
56 Rutanen J. Vascular Endothelial Growth Factors in Atherosclerosis and Gene Therapy for Restenosis and Myocardial Ischemia.
57 Rutanen J et al. Gene transfer using the mature form of VEGF-D reduces neointimal thickening through nitric oxide-dependent mechanism.
58 Saaristo A et al. Gene transfer as a tool to induce therapeutic vascular growth in plastic surgery.
59 Salminen M et al. Improvement in nuclear entry and transgene expression of baculoviruses by disintegration of microtubules.
60 Tammela T et al. Angiopoietin-1 promotes lymphatic sprouting and hyperplasia.
61 Tucker JM et al. Potent modulation of intestinal tumorigenesis in Apcmin/+ mice by the polyamine catabolic enzyme spermidine/spermine N1-acetyltransferase.
62 Tuomisto TT et al. Genetics, genomics and proteomics in atherosclerosis research.
63 Tuomisto TT et al. Analysis of gene and protein expression during monocyte-macrophage differentation and cholesterol loading - cDNA and protein array study.
64 Tuomisto TT, Ylä-Herttuala S. What have we learnt about microarray analyses of atherogenesis?
65 Turunen P. Gene Therapy of Restenosis and Vein Graft Disease Studies With Single Genes and Gene Combinations.
66 Turunen P et al. Intravascular adenovirus-mediated lipoprotein-associated phospholipase A2 gene transfer reduces neointima formation in balloon-denuded rabbit aorta.
67 Vähäkangas E, Ylä-Herttuala S. Gene therapy of atherosclerosis.
68 Walkowiak J et al. Fecal pyruvate kinase (M2-PK): A new predictor for inflammation and severity of pouchitis.
69 Walkowiak J et al. Early decline of pancreatic function in cystic fibrosis patients with class 1 or 2 CFTR mutations.
70 Wu JC, Ylä-Herttuala S. Human gene therapy and imaging: cardiology.
71 Yu H-G et al. Valine-286 residue in the third intracellular loop of the cholecystokinin 2 receptor exerts a pivotal role in cholecystokinin 2 receptor mediated intracellular signal transduction in human colon cancer cells.

Bioteknologian ja molekulaarisen lääketieteen laitos Department of Biotechnology and Molecular Medicine
Julkaisutietokanta 15.4.2008 Publications Data Base 15.4.2008