A.I. Virtanen -instituutti
A.I. Virtanen Institute for Molecular Sciences

Julkaisut 2003
Publications 2003

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1 Airenne KJ et al. Improved generation of recombinant baculovirus genomes in Escherichia coli.
2 Allart B et al. A stable bis-allyloxycarbonyl biotin aldehyde derivative for biotinylation via reductive alkylation: application to the synthesis of a biotinylated doxorubicin derivative.
3 Ammoun S et al. Distinct recognition of OX1 and OX2 receptors by orexin peptides.
4 Barker SD et al. The secretory leukoprotease inhibitor (SLPI) promoter for ovarian cancer gene therapy.
5 Bhardwaj S et al. Angiogenic responses of vascular endothelial growth factors in periadventitial tissue.
6 Bräsen JH et al. Patterns of oxidized epitopes, but not NF-kappaB expression, change during atherogenesis in WHHL rabbits.
7 Griffin JL et al. Assignment of 1H nuclear magnetic resonance visible polyunsaturated fatty acids in BT4C gliomas undergoing ganciclovir-thymidine kinase gene therapy-induced programmed cell death.
8 Gröhn H. A Study of T1 rho Relaxation: From Relaxation Mechanisms to the Magnetic Resonance Imaging Contrast.
9 Gröhn OHJ et al. On- and off-resonance T1rho MRI in acute cerebral ischemia of the rat.
10 Gröhn OHJ et al. Novel magnetic resonance imaging contrasts for monitoring response to gene therapy in rat glioma.
11 Grönlund-Pakkanen S et al. The effect of photodynamic therapy on rat urinary bladder with orthotopic urothelial carcinoma.
12 Haapasalo A. Localization and Function of trkB Neurotrophin Receptor Isoforms in Neuronal Cells.
13 Hakkarainen T et al. CD40 is expressed on ovarian cancer cells and can be utilized for targeting andenoviruses.
14 Hakumäki JM, Brindle KM. Techniques: Visualizing apoptosis using nuclear magnetic resonance.
15 Hedman M et al. Safety and feasibility of catheter-based local intracoronary vascular endothelial growth factor gene transfer in the prevention of postangioplasty and in-stent restenosis and in the treatment of chronic myocardial ischemia: phase II [...].
16 Heikkilä A. Experimental Strategies for Placental Gene Transfer and Gene Expression in Preeclamptic Placenta.
17 Heikkinen P et al. Effects of mobile phone radiation on UV-induced skin tumourigenesis in ornithine decarboxylase transgenic and non-transgenic mice.
18 Hemminki A et al. Production of an EGFR targeting molecule from a conditionally replicating adenovirus impairs its oncolytic potential.
19 Hiltunen MO et al. Adenovirus-mediated VEGF-A gene transfer induces bone formation in vivo.
20 Hiltunen MO, Ylä-Herttuala S. DNA methylation, smooth muscle cells. and atherogenesis.
21 Hongisto V et al. Lithium blocks the c-Jun stress response and protects neurons via its action on glycogen synthase kinase 3.
22 Iivanainen E et al. Angiopoietin-regulated recruitment of vascular smooth muscle cells by endothelial-derived heparin binding EGF-like growth factor.
23 Jalkanen J et al. Adeno-associated virus-mediated gene transfer of a secreted decoy human macrophage scavenger receptor reduces atherosclerotic lesion formation in LDL receptor knockout mice.
24 Jalkanen J et al. Adenovirus-mediated gene transfer of a secreted decoy human macrophage scavenger receptor (SR-AI) in LDL receptor knock-out mice.
25 Jänne J, Alhonen L. Muuntogeeniset eläimet muulistavat biologista tutkimusta.
26 Kaasinen SK et al. Overexpression of spermidine/spermine N1-acetyltransferase elevates the threshold to pentylenetetrazol-induced seizure activity in transgenic mice.
27 Kanerva A et al. Enhanced therapeutic efficacy for ovarian cancer with a serotype 3 receptor-targeted oncolytic adenovirus.
28 Kankainen M, Wong G. DANCER: a program for digital anatomical reconstruction of gene expression data.
29 Karhunen H et al. Long-term functional consequences of transient occlusion of the middle cerebral artery in rats: a 1-year follow-up of the development of epileptogenesis and memory impairment in relation to sensorimotor deficits.
30 Kaski S et al. Trustworthiness and metrics in visualizing similarity of gene expression.
31 Kleinman NS et al. Evolving revascularization approaches for myocardial ischemia.
32 Koponen JK et al. Doxycycline-regulated lentiviral vector system with a novel reverse transactivator rtTA2S-M2 shows a tight control of gene expression in vitro and in vivo.
33 Koponen S et al. Prevention of NMDA-induced death of cortical neurons by inhibition of protein kinase Czeta.
34 Kossila M et al. Promoter polymorphisms -359T/C and -303A/G of the catalytic subunit p110beta gene of human phosphatidylinositol 3-kinase are not associated with insulin secretion or insulin sensitivity in Finnish subjects.
35 Kukkonen SP et al. Baculovirus capsid display: a novel tool for transduction imaging.
36 Laitinen OH et al. Rational design of an active avidin monomer.
37 Lakso M et al. Dopaminergic neuronal loss and motor deficits in Caenorhabditis elegans overexpressing human alfa-synuclein.
38 Lampela P et al. Production of functional recombinant tyrosine hydroxylase by the BPV-1 expression plasmids in the cell cultures.
39 Larsson KP et al. The STC-1 cells express functional orexin-A receptors coupled to CCK release.
40 Laurema A et al. Transfection of oocytes and other types of ovarian cells in rabbits after direct injection into uterine arteries of adenoviruses and plasmid/liposomes.
41 Laurén HB et al. Selective changes in gamma-aminobutyric acid type A receptor subunits in the hippocampus in spontaneously seizing rats with chronic temporal lobe epilepsy.
42 Lehtimäki KK et al. Metabolite changes in BT4C rat gliomas undergoing ganciclovir-thymidine kinase gene therapy-induced programmed cell death as studied by 1H NMR spectroscopy in vivo, ex vivo, and in vitro*.
43 Lehtolainen P et al. Targeting of biotinylated compounds to its target tissue using a low-density lipoprotein receptor-avidin fusion protein.
44 Liuba P et al. Acute infections in children are accompanied by oxidative modification of LDL and decrease of HDL cholesterol, and are followed by thickening of carotid intima-media.
45 Liuba P et al. Co-infection with Chalamydia pneumoniae and Helicobacter pylori results in vascular endothelial dysfunction and enhanced VCAM-1 expression in apoE-knockout mice.
46 Lucas G et al. Neurotrophin-4 mediated TrkB activation reinforces morphine-indiced analgesia.
47 Lukasiuk K et al. cDNA profiling of epileptogenesis in the rat brain.
48 Lähteinen S et al. Exacerbated status epilepticus and acute cell loss, but no changes in epileptogenesis, in mice with increased brain-derived neurotrophic factor signaling.
49 Majak K, Pitkänen A. Activation of the amygdalo-entorhinal pathway in fear-conditioning in rat.
50 Majak K, Pitkänen A. Projections from the periamygdaloid cortex to the amygdaloid complex, the hippocampal formation, and the parahippocampal region: A PHA-L study in the rat.
51 Marvanová M. Genomic Approaches to Access the Effects of Neuroprotective Drugs and Validity of Nonhuman Primate Models in Neurodegenerative Diseases.
52 Marvanová M et al. Microarray analysis of nonhuman primates: validation of experimental models in neurological disorders.
53 Marvanová M et al. Microarray data analysis - applications for studies on gene expression in addiction and human/nonhuman primates.
54 Matyjek R et al. Exogenous leptin inhibits the secretion of pancreatic juice via a duodenal CCK(1)-vagal-dependent mechanism in anaesthetized rats.
55 Narkilahti S et al. Administration of caspase 3 inhibitor during and after status epilepticus in rat: effect on neuronal damage and epileptogenesis.
56 Narkilahti S et al. Expression and activation of caspase 3 following status epilepticus in the rat.
57 Niittykoski M et al. Selegiline reduces N-methyl-D-aspartic acid induced perturbation of neurotransmission but it leaves NMDA receptor dependent long-term potentiation intact in the hippocampus.
58 Niskanen L et al. Association of the PRO12ALA polymorphism of the PPAR-gamma2 gene with oxidized low-density lipoprotein and cardiolipin autoantibodies in nondiabetic and type 2 diabetic subjects.
59 Nordlund HR et al. Introduction of histidine residues into avidin subunit interfaces allows pH-dependet regulation of quaternary structure and biotin binding.
60 Nykänen AI et al. Angiopoietin-1 protects against the development of cardiac allograft arteriosclerosis.
61 Oker-Blom C et al. Baculovirus display strategies: Emerging tools for eukaryotic libraries and gene delivery.
62 Otte J-M et al. Antimicrobial peptides in innate immunity of the human intestine.
63 Otte J-M et al. Expression of functional prolactin and its receptor in human colorectal cancer.
64 Otte J-M et al. Gastrointestinal hormone-releasing peptides.
65 Pasanen T et al. TK-GFP fusion gene virus vector as tools for studying the features of HSV-TK/ganciclovir cancer gene therapy in vivo.
66 Pasanen T et al. Polyamine biosynthesis inhibition enhances HSV-1 thymidine kinase/ganciclovir-mediated cytotoxity in tumor cells.
67 Pels K et al. Effect of adventitial VEGF165 gene transfer on vascular thickening after coronary artery balloon injury.
68 Penttonen M, Buzsáki G. Natural logarithmic relationship between brain oscillators.
69 Pitkänen A. Tunteiden neurobiologiaa.
70 Pitkänen A. Clinical trials in neuroprotection.
71 Pitkänen A. American Epilepsy Society - 56th Annual Meeting.
72 Pitkänen A et al. Intrinsic synaptic circuitry of the amygdala.
73 Rissanen T. Gene Transfer for Blood and Lymphatic Vessel Growth.
74 Rissanen TT et al. Fibroblast growth factor-4 induces vascular permeability, angiogenesis, and arteriogenesis in a rabbit hind limb ischemia model.
75 Rissanen TT et al. VEGF-D is the strongest angiogenic and lymphangiogenic effector among VEGFs delivered into skeletal muscle via adenoviruses.
76 Rossi J et al. Alimentary tract innervation deficits and dysfunction in mice lacking GDNF family receptor alpha2.
77 Rubanyi GM, Ylä-Herttuala S. Preface.
78 Rutanen J et al. Vascular endothelial growth factor-D expression in human atherosclerotic lesions.
79 Räsänen T-L. Transgenic Rats with Activated Polyamine Catabolism. Spermidine Depletion Inhibits Hepatic Cell Proliferation and Causes Acute Pancreatitis.
80 Räsänen T-L et al. Gossypol activates pancreatic polyamine catabolism in normal rats and induces acute pancreatitis in transgenic rats over-expressing spermidine/spermine N1-acetyltransferase.
81 Saarelainen T et al. Activation of the TrkB neurotrophin receptor is induced by antidepressant drugs and is required for antidepressant-induced behavioral effects.
82 Shan J et al. Tissue-specific expression of the prostatic acid phosphatase promoter constructs.
83 Shinnick-Gallagher P et al., ed. The Amygdala in Brain Function: Basic and Clinical Approaches.
84 Silvennoinen MJ et al. Comparison of the dependence of blood R2 and R2* on oxygen saturation at 1.5 and 4.7 Tesla.
85 Silvennoinen MJ et al. Effects of hematocrit and oxygen saturation level on blood spin-lattice relaxation.
86 Stables JP et al. Therapy discovery for pharmacoresistant epilepsy and for disease-modifying therapeutics: summary of the NIH/NINDS/AES models II workshop.
87 Storvik M et al. Subunit selective decrease of AMPA and metabotropic glutamate receptor mRNA expression in rat brain by systemic administration of the NMDA receptor blocker MK-801.
88 Sutula TP et al. Do epileptic seizures damage the brain?
89 Tarkka T et al. Adenoviral VEGF-A gene transfer induces angiogenesis and promotes bone formation in healing osseous tissues.
90 Tran SEF et al. Heat stress downregulates FLIP and sensitizes cells to Fas receptor-mediated apoptosis.
91 Tuomisto TT et al. Gene expression in macrophage-rich inflammatory cell infiltrates in human atherosclerotic lesions as studied by laser microdissection and DNA array.
92 Tuomisto TT, Ylä-Herttuala S. Genes involved in atherosclerosis and plaque formation.
93 Turunen MP et al. Cardiovascular gene therapy.
94 Tuunanen PI et al. Comparison of BOLD fMRI and MEG characteristics to vibrotactile stimulation.
95 Törönen P et al. Methods for quantitation and clustering of gene expression data.
96 Vartiainen N et al. Aspirin inhibits p44/42 mitogen-activated protein kinase and is protective against hypoxia/reoxygenation neuronal damage.
97 Väisänen J et al. Altered trkB neurotrophin receptor activation does not influence the N-methyl-D-aspartate receptor antagonist-mediated neurotoxicity in mouse posterior cingulate cortex.
98 Walkowiak J et al. Longitudinal follow-up of exocrine pancreatic function in pancreatic sufficient cystic fibrosis patients using the fecal elastase-1 test.
99 Walkowiak J et al. Inhibition of endogenous pancreatic enzyme secretion by oral pancreatic enzyme treatment.
100 Wong G. Introduction.
101 Wong G. Experimental design.
102 Ylä-Herttuala S. Hero or villain?
103 Ylä-Herttuala S. Angiogenesis clinical trials.
104 Ylä-Herttuala S. Percutaneous transcoronary venous access for cellular cardiomyoplasty.
105 Ylä-Herttuala S. A New Class of Biological Agents. The Design, Development and Testing of Ad5FGF-4 to Treat Ischaemic Heart Disease.
106 Ylä-Herttuala S. The Foundation of a Medical Revolution.
107 Ylä-Herttuala S. Novel targeting of biotinylated compounds to local tissues with avidin-lipoprotein receptor fusion protein.
108 Ylä-Herttuala S, Alitalo K. Gene transfer as a tool to induce therapeutic vascular growth.

A.I. Virtanen -instituutti A.I. Virtanen Institute for Molecular Sciences
Julkaisutietokanta 15.4.2008 Publications Data Base 15.4.2008