A.I. Virtanen -instituutti
A.I. Virtanen Institute for Molecular Sciences

Julkaisut 2002
Publications 2002

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1 Alhonen L et al. Polyamines are required for the initiation of rat liver regeneration.
2 Barbelivien A et al. Differentially altered cerebral metabolism in ischemic rats by alfa2-adrenoceptor blockade and its relation to improved limb-placing reactions.
3 Bräsen JH et al. Comparison of the effects of alpha-tocopherol, ubiquinone-10 and probucol at therapeutic doses on atherosclerosis in WHHL rabbits.
4 Castrén M et al. BDNF regulates the expression of fragile X mental retardation protein mRNA in the hippocampus.
5 Coffey ET et al. c-Jun N-terminal protein kinase (JNK) 2/3 is specifically activated by stress, mediating c-Jun activation, in the presence of constitutive JNK1 activity in cerebellar neurons.
6 Gao Z-H et al. Association of H19 promoter methylation with the expression of H19 and IGF-II genes in adrenocortical tumors.
7 Gimelli G et al. Gene dosage of the spermidine/spermine N1-acetyltransferase (SSAT) gene with putrescine accumulation in a patient with a Xp21.12 duplication and keratosis follicularis spinulosa decalvans (KFSD).
8 Grönlund-Pakkanen S et al. The fluorescence biodistribution and kinetics of aminolevulinic acid induced protoporphyrin IX in the bladder of a rat model with orthotopic urothelial carcinoma.
9 Haapasalo A et al. Regulation of TRKB surface expression by brain-derived neurotrophic factor and truncated TRKB isoforms.
10 Hakumäki JM et al. Early gene therapy - induced apoptotic response in BT4C gliomas by magnetic resonance relaxation contrast T1 in the rotating frame.
11 He Y et al. Suppression of tumor lymphangiogenesis and lymph node metastasis by blocking vascular endothelial growth factor receptor 3 signaling.
12 Heikkilä A et al. Gene transfer to human placenta ex vivo: A novel application of dual perfusion of human placental cotyledon.
13 Hiltunen MO et al. Changes in gene expression in atherosclerotic plaques analyzed using DNA array.
14 Hiltunen MO et al. DNA hypomethylation and methyltransferase expression in atherosclerotic lesions.
15 Hiltunen Y et al. Quantification of human brain metabolites from in vivo1H NMR magnitude spectra using automated artificial neural network analysis.
16 Holmqvist T et al. Orexin signaling in recombinant neuron-like cells.
17 Jolkkonen E et al. Projections from the amygdaloid complex to the magnocellular cholinergic basal forebrain in rat.
18 Jutila L et al. Neurobiology of epileptogenesis in the temporal lobe.
19 Kaasinen SK et al. Induction and activation of protein kinase Cdelta in hippocampus and cortex after kainic acid treatment.
20 Kauppinen RA. Monitoring cytotoxic tumour treatment response by diffusion magnetic resonance imaging and proton spectroscopy.
21 Kemppainen S et al. Projections from the posterior cortical nucleus of the amygdala to the hippocampal formation and parahippocampal region in rat.
22 Kettunen M. A Study of Magnetic Resonance Imaging Contrast Generation and Pathophysiology in Acute Cerebral Ischaemia.
23 Kettunen MI et al. Effects of intracellular pH, blood, and tissue oxygen tension on T-1rho relaxation in rat brain.
24 Kettunen MI et al. Quantitative assessment of the balance between oxygen delivery and consumption in the rat brain after transient ischemia with T2-BOLD magnetic resonance imaging.
25 Koistinaho J. Neuroprotection with tetracyclines in brain ischemia models.
26 Koistinaho M et al. Beta-amyloid precursor protein transgenic mice that harbor diffuse A beta deposits but do not form plaques show increased ischemic vulnerability: Role of inflammation.
27 Koistinaho M et al. Expression of human apolipoprotein E downregulates amyloid precursor protein-induced ischemic susceptibility.
28 Koistinaho M, Koistinaho J. Role of p38 and p44/42 mitogen-activated protein kinases in microglia.
29 Kontkanen O. Gene Expression in Rat Brain: Alterations by Antipsychotic Drugs.
30 Kontkanen O, Castrén E. Functional genomics in neuropsychiatric disorders and in neuropharmacology.
31 Kontkanen O et al. Chronic antipsychotic drug treatment induces long-lasting expression of fos and jun family genes and activator protein 1 complex in the rat prefrontal cortex.
32 Kontkanen O et al. Antipsychotic drug treatment induces differential gene expression in the rat cortex.
33 Koponen JK et al. Escherichia coli DNA contamination in AmpliTag Gold polymerase interferes with TagMan analysis of IacZ.
34 Korolainen MA et al. Proteomic analysis of protein in Alzheimer's disease brain .
35 Kossila M et al. Improvement in adenoviral gene transfer efficiency after preincubation at +37oC in vitro and in vivo.
36 Kubová H et al. Dynamic changes of status epilepticus-induced neuronal degeneration in the mediodorsal nucleus of the thalamus during postnatal development of the rat.
37 Kuhmonen J et al. Diazepam does not reduce infarct size in rats subjected to transient occlusion of the middle cerebral artery when normothermia is maintained.
38 Kukkonen JP et al. Functions of the orexinergic/hypocretinergic system.
39 Kumlin T et al. p53-independent apoptosis in UV-irradiated mouse skin: possible inhibition by 50 Hz magnetic fields.
40 Kurkinen K. Molecular Cloning of the Brain Ischemia - Inducible Rat Protein Kinase C delta (PKCdelta) and its Activation in Neuronal Preconditioning Models.
41 Lampela P et al. The use of low-molecular-weight PEIs as gene carriers in the monkey fibroblastoma and rabbit smooth muscle cell cultures.
42 Laukkanen J, Ylä-Herttuala S. Genes involved in atherosclerosis.
43 Laukkanen J, Ylä-Herttuala S. Cloning and characterization of soluble decoy receptors.
44 Laukkanen MO et al. Adenovirus-mediated extracellular superoxide dismutase gene therapy reduces neointima formation in balloon-denuded rabbit aorta.
45 Lehtolainen P. Lipoprotein Receptor -Avidin Fusion Proteins. A New Concept for Drug Targeting.
46 Lehtolainen P et al. Cloning and characterization of Scavidin, a fusion protein for the targeted delivery of biotinylated molecules.
47 Lehtolainen P et al. Baculoviruses exhibit restricted cell type specificity in rat brain: a comparison of baculovirus- and adenovirus-mediated intracerebral gene transfer in vivo.
48 Lemström KB et al. Vascular endothelial growth factor enhances cardiac allograft arteriosclerosis.
49 Lukasiuk K et al. Upregulation of cystatin C expression in the rat hippocampus during epileptogenesis in the amygdala stimulation model of temporal lobe epilepsy.
50 Lähteinen S et al. Decreased BDNF signalling in transgenic mice reduces epileptogenesis.
51 Majak K et al. Projections from the amygdaloid complex to the claustrum and the endopiriform nucleus: a Phaseolus vulgaris leucoagglutinin study in the rat.
52 Marvanova M et al. Synexpression analysis of ESTs in the rat brain reveals distinct patterns and potential drug targets.
53 Mikkonen JE et al. Hippocampus retains the periodicity of gamma stimulation in vivo.
54 Mikkonen JE et al. Probabilistic design of long quantization error free fixed-point polynomial predictors.
55 Min SH et al. Altered levels of growth-related and novel gene transcripts in reproductive and other tissues of female mice overexpressing spermidine/spermine N1-acetyltransferase (SSAT).
56 Mäkelä HI et al. Quantitative T (1rho) and magnetization transfer magnetic resonance imaging of acute cerebral ischemia in the rat.
57 Mäkinen K et al. Increased vascularity detected by digital subtraction angiography after VEGF gene transfer to human lower limb artery: A randomized, placebo-controlled, double-blinded phase II study.
58 Niemi M et al. Apolipoprotein E and colon cancer. Expression in normal and malignant human intestine and effect on cultured human colonic adenocarcinoma cells.
59 Nieminen MT et al. Spatial assessment of articular cartilage proteoglycans with Gd-DTPA-enhanced T1 imaging.
60 Niiranen K et al. Targeted disruption of spermidine/spermine N1-acetyltransferase gene in mouse embryonic stem cells.
61 Nikkilä J et al. Analysis and visualization of gene expression data using self-organizing maps.
62 Näsman J et al. Different roles for Gi and Go proteins in modulation of adenylyl cyclase type-2 activity.
63 Oja M et al. Exploratory clustering on gene expression profiles of mutated yeast strains.
64 Olkkonen H et al. EEG noise cancellation by a subspace method based on wavelet decomposition .
65 Pajusola K et al. Cell-type-specific characteristics modulate the transduction efficiency of adeno-associated virus type 2 and restrain infection of endothelial cells.
66 Petrova TV et al. Lymphatic endothelial reprogramming of vascular endothelial cells by the Prox-1 homeobox transcription factor.
67 Pitkanen A et al. Projections from the lateral, basal, and accessory basal nuclei of the amygdala to the entorhinal cortex in the macaque monkey.
68 Pitkänen A. Efficacy of current antiepileptics to prevent neurodegeneration in epilepsy models.
69 Pitkänen A. Prevention of epileptogenesis.
70 Pitkänen A. Drug-mediated neuroprotection and anti-epileptogenesis.
71 Pitkänen A, Kemppainen S. Comparison of the distribution of calcium-binding proteins and intrinsic connectivity in the lateral nucleus of the rat, monkey, and human amygdala.
72 Pitkänen A et al. Progression of neuronal damage after status epilepticus and during spontaneous seizures in a rat model of temporal lobe epilepsy.
73 Pitkänen A, Sutula TP. Is epilepsy a progressive disorder? Prospects for new therapeutic approaches in temporal-lobe epilepsy.
74 Pulkkanen KJ et al. The combination of HSV-tk and endostatin gene therapy eradicates orthotopic human renal cell carcinomas in nude mice.
75 Rissanen TT et al. Expression of vascular endothelial growth factor and vascular endothelial growth factor receptor-2 (KDR/Flk-1) in ischemic skeletal muscle and its regeneration.
76 Rutanen J et al. Gene therapy for restenosis. Current status.
77 Rutanen J et al. Post-intervention vessel remodeling.
78 Räsänen T-L et al. A polyamine analogue prevents acute pancreatitis and restores early liver regeneration in transgenic rats with activated polyamine catabolism.
79 Saaristo A et al. Adenoviral VEGF-C overexpression induces blood vessel enlargement, tortuosity, and leakiness but no sprouting angiogenesis in the skin or mucous membranes.
80 Saaristo A et al. Lymphangiogenic gene therapy with minimal blood vascular side effects.
81 Silvennoinen J. A Study of NMR Relaxation in Blood. Mechanistic Considerations and Implications for Quantitative Functional MRI.
82 Silvennonen MJ et al. Blood NMR relaxation in the rotating frame: mechanistic implications.
83 Solovyan VT et al. The role of topoisomerase II in the excision of DNA loop domains during apoptosis.
84 Stoilov P et al. Analysis of the human TrkB gene genomic organization reveals novel TrkB isoforms, unusual gene length, and splicing mechanism.
85 Suppola S. Consequences of Activated Polyamine Catabolism. Experimental Studies in Transgenic Mice and a Human Case Report.
86 Tikka TM et al. Minocycline prevents neurotoxicity induced by cerebrospinal fluid from patients with motor neurone disease.
87 Turunen MP et al. Local cardiovascular gene therapy.
88 Turunen MP et al. Peptide-retargeted adenovirus encoding a tissue inhibitor of metalloproteinase-1 decreases restenosis after intravascular gene transfer.
89 Tyynelä K et al. Adenovirus-mediated herpes simplex virus thymidine kinase gene therapy in BT4C rat glioma model.
90 Törönen P et al. Expression profiling to understand actions of NMDA/glutamate receptor antagonists in rat brain.
91 Vajanto I et al. Evaluation of angiogenesis and side effects in ischemic rabbit hindlimbs after intramuscular injection of adenoviral vectors encoding VEGF and LacZ.
92 Vartiainen N et al. Aspirin provides cyclin-dependent kinase 5-dependent protection against subsequent hypoxia/reoxygenation damage in culture.
93 Wahlfors J, Morgan RA. Minigene-containing retroviral vectors using an alphavirus/retrovirus hybrid vector system. Production and use.
94 Wahlfors J, Morgan RA. Semliki forest virus vectors for gene transfer.
95 Walkowiak J et al. Fecal elastase-1 is superior to fecal chymotrypsin in the assessment of pancreatic involvement in cystic fibrosis.
96 Ylä-Herttuala S. Therapeutic angiogenesis: How far from clinical practice?

A.I. Virtanen -instituutti A.I. Virtanen Institute for Molecular Sciences
Julkaisutietokanta 15.4.2008 Publications Data Base 15.4.2008