to use interdisciplinary
expertise in applying standardized protocols to study the impact of
dietary sensing by NRs on the genome, epigenome, transcriptome,
proteome, metabolome and physiome, and thereby model these actions in
different human tissues.
use intersectorial expertise in revealing the significance of
NR-nutrient signaling in pathological conditions associated with aging,
such as carcinogenesis, metabolic syndromes, osteoporosis and aging
generate an interdisciplinary and intersectorial understanding using
systems biology modelling with the aims of i) revealing a predicative
and preventative ultimately personalized paradigm for the effect of diet
upon key aspects of health within the aging European population and ii)
generating commercial realization.