Bioteknologian ja molekulaarisen lääketieteen laitos
Department of Biotechnology and Molecular Medicine

Julkaisut 2007 (alustava)
Publications 2007 (preliminary)

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1 Aggarwal NT et al. Adenoviral expression of 15-lipoxygenase-1 in rabbit aortic endothelium: role in arachidonic acid-induced relaxation.
2 Airenne KJ et al. Safe, simple, and high-capacity gene delivery into insect and vertebrate cells by recombinant baculoviruses.
3 Back J et al. Solusiirrot sydämen vajaatoiminnan hoidossa.
4 Bengtsson MW et al. Food-induced expression of orexin receptors in rat duodenal mucosa regulates the bicarbonate secretory response to orexin-A.
5 Bräsen JH et al. Extracellular superoxide dismutase accelerates endothelial recovery and inhibits in-stent restenosis in stented atherosclerotic Watanabe heritable hyperlipidemic rabbit aorta.
6 Czub E et al. Fecal pyruvate kinase: A potential new marker for intestinal inflammation in children with inflammatory bowel disease.
7 Degenhardt T et al. Three members of the human pyruvate dehydrogenase kinase gene family are direct targets of the peroxisome proliferator-activated receptor beta/delta.
8 Ellrichmann M et al. Orlistat reduces gallbladder emptying by inhibition of CCK release in response to a test meal.
9 Fueger PT et al. Phosphorylation barriers to skeletal and cardiac muscle glucose uptakes in high-fat-fed mice. Studies in mice with a 50 % reduction of hexokinase II.
10 Gofflot F et al. Systematic gene expression mapping clusters nuclear receptors according to their function in the brain.
11 Grigorenko NA et al. Synthesis of novel optical isomers of [alpha]-methylpolyamines.
12 Heikkinen S et al. PPARgamma in human and mouse physiology.
13 Heinonen MV et al. Plasma ghrelin levels after two high-carbohydrate meals producing different insulin responses in patients with metabolic syndrome.
14 Heinonen SE et al. Increased atherosclerotic lesion calcification in a novel mouse model combining insulin resistance, hyperglycemia, and hypercholesterolemia.
15 Helppolainen SH et al. Rhizavidin from Rhizobium etli: the first natural dimer in the avidin protein family.
16 Hyvönen MT. Regulation of Spermidine/Spermine N1-Acetyltransferase and its Involvement in Cellular Proliferation and Development of Acute Pancreatitis.
17 Hyvönen MT et al. Role of hypusinated eukaryotic translation initiation factor 5A in polyamine depletion-induced cytostasis.
18 Hyvönen MT et al. Mechanisms of polyamine catabolism-induced acute pancreatitis.
19 Häkkinen MR et al. Analysis of underivatized polyamines by reversed phase liquid chromatography with electorspray tandem mass spectrometry.
20 Jell J et al. Genetically altered expression of spermidine/spermine N1-acetyltransferase affects fat metabolism in mice via acetyl-CoA.
21 Keinänen R et al., ed. The First Annual Post-Graduate Symposium of the Graduate School of Molecular Medinie.
22 Keinänen TA et al. Alpha-methylated polyamines as potential drugs and experimental tools in enzymology.
23 Keskitalo S et al. Enhanced capillary formation stimulated by a chimeric vascular endothelial growth factor/vascular endothelial growth factor-C silk domain fusion protein.
24 Kettunen MI et al. Low spin-lock field T1 relaxation in the rotating frame as a sensitive MR imaging marker for gene therapy treatment response in rat glioma.
25 Kholová I et al. Adenovirus-mediated gene transfer of human vascular endothelial growth factor-d induces transient angiogenic effects in mouse hind limb muscle.
26 Kiehne K et al. Antimicrobial peptides in chronic anal fistula epithelium.
27 Koponen JK et al. Umbilical cord blood-derived progenitor cells enhance muscle regeneration in mouse hindlimb ischemia model.
28 Korpisalo P et al. The strengths and weaknesses of VEGF adenovirus-driven angiogenesis.
29 Laurema A et al. Transduction patterns and efficiencies in rabbit uterine tissues after intraluminal uterine adenovirus administration vary with the reproductive cycle.
30 Leppänen P. Mouse Models of Atherosclerosis, Vascular Endothelial Growth Factors and Gene Therapy.
31 Levonen A-L et al. Nrf2 gene transfer induces antioxidant enzymes and suppresses smooth muscle cell growth in vitro and reduces oxidative stress in rabbit aorta in vivo.
32 Liimatainen T. Molecular Magnetic Resonance Imaging of Gene Therapy-induced Apoptosis and Gene Transfer. A Role for 1H Spectroscopic Imaging and Iron Oxide Labelled Viral Particles.
33 Liuba P et al. Residual adverse changes in arterial endothelial function and LDL oxidation after a mild systemic inflammation induced by influenza vaccination.
34 Lucerna M et al. Vascular endothelial growth factor-A induces plaque expansion in ApoE knock-out mice by promoting de novo leukocyte recruitment.
35 Merentie M et al. Oxidative stress and inflammation in the pathogenesis of activated polyamine catabolism-induced acute pancreatitis.
36 Mähönen AJ et al. Post-transcriptional regulatory element boosts baculovirus-mediated gene expression in vertebrate cells.
37 Määttä A-M. Development of Gene and Virotherapy Against Non-Small Cell Lung Cancer.
38 Määttä A-M et al. Evaluation of cancer virotherapy with attenuated replicative Semliki Forest virus on different rodent tumor models.
39 Otte J-M et al. Differential regulated expression of keratinocyte growth factor and its receptor in experimental and human liver fibrosis.
40 Pirinen E et al. Enhanced polyamine catabolism alters homeostatic control of white adipose tissue mass, energy expenditure, and glucose metabolism.
41 Raisky O et al. VEGFR-1 and -2 regulate inflammation, myocardial angiogenesis, and arteriosclerosis in chronically rejecting cardiac allografts.
42 Rautsi O. Hurdles and Improvements in Therapeutic Gene Transfer for Cancer.
43 Rissanen TT, Ylä-Herttuala S. Uudisverisuonten kasvattaminen - kohti iskeemisten kudosten parempaa verenkiertoa.
44 Rissanen TT, Ylä-Herttuala S. Current status of cardiovascular gene therapy.
45 Räty JK et al. SPECT/CT imaging of baculovirus biodistribution in rat.
46 Räty JK et al. Non-invasive imaging in gene therapy.
47 Räty S et al. Screening for human cationic trypsinogen (PRSS1) and trypsinogen inhibitor gene (SPINK1) mutations in a Finnish family with hereditary pancreatitis.
48 Siiskonen H et al. Diazepam binding inhibitor overexpression in mice causes hydrocephalus, decreases plasticity in excitatory synapses and impairs hippocamus-depend learning.
49 Simonian A et al. Novel CoA-polyamine conjugates for effective inhibition of spermine/spermidine-N1-acetyltransferase.
50 Sipola A et al. Endostatin inhibits endochondral ossification.
51 Tammela T et al. Distinct architecture of lymphatic vessels induced by chimeric vascular endothelial growth factor-C/vascular endothelial growth factor heparin-binding domain fusion proteins.
52 Tammela T et al. Therapeutic differentiation and maturation of lymphatic vessels after lymph node dissection and transplantation.
53 Wirzenius M et al. Distinct vascular endothelial growth factor signals for lymphatic vessel enlargement and sprouting.
54 Yan D et al. Oxysterol binding protein induces upregulation of SREBP-1c and enhances hepatic lipogenesis.
55 Ylä-Herttuala S. Principles of gene medicines.
56 Ylä-Herttuala S. Peripheral vascular diseases. In Review: Progress and prospects: gene therapy clinical trials (Part 1).
57 Ylä-Herttuala S, Alitalo K. On the relationship of LDL and VEGFR1: not just a family affair.
58 Ylä-Herttuala S et al. Vascular endothelial growth factors. Biology and current status of clinical applications in cardiovascular medicine.

Bioteknologian ja molekulaarisen lääketieteen laitos Department of Biotechnology and Molecular Medicine
Julkaisutietokanta 16.4.2008 Publications Data Base 16.4.2008