Farmaseuttisen kemian laitos
Department of Pharmaceutical Chemistry

Julkaisut 2006
Publications 2006

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1 Callaway JC. The medicinal uses of cannabis and cannabinoids.
2 Callaway JC et al. A demand for clarity regarding a case report on the ingestion of 5-methoxy-N, N-dimethyltryptamine (5-MeO-DMT) in an ayahuasca preparation.
3 Chuvikovsky DV et al. Ribokinase from E. coli: expression, purification, and substrate specificity.
4 Dahlén K et al. Synthesis of 2,3,6,8-tetrasubstituted chromone scaffolds.
5 Holappa J. Design, Synthesis and Characterization of Novel Water-Soluble Chitosan Derivates.
6 Holappa J et al. Antimicrobial activity of chitosan N-betainates.
7 Holappa J et al. Novel water-soluble quaternary piperazine derivatives of chitosan: synthesis and characterization.
8 Holappa J et al. A novel and selective synthesis of di- and trimethylpiperazinium acetic acid iodide salts.
9 Holappa J et al. Synthesis of novel quaternary chitosan derivatives via N-Chloroacyl-6-O-triphenylmethylchitosans.
10 Holoppa J et al. Synthesis and characterization of novel water-soluble quaternary piperazine derivatives of chitosan.
11 Huhtiniemi T et al. Comparative and pharmacophore model for deacetylase SIRT1.
12 Huttunen KM et al. Efficient strategy to prepare water-soluble prodrugs of ketones.
13 Jarho EM et al. An introduction of a pyridine group into the structure of prolyl oligopeptidase inhibitors.
14 Jäppinen AL. Stability of Hospital Pharmacy-prepared Analgesic Mixtures Administered by a Continuous Infusion .
15 Järvinen T. Farmasian tohtorikoulutus on elintärkeää alan kehittämiselle.
16 Järvinen T et al., inventor. Novel methylated cyclodextrin complexes.
17 Järvinen T et al., inventor. New pharmaceutical compounds with alpha2receptor activity.
18 Kiviranta PH et al. N,N´-bisbenzylidenebenzene-1,4-diamines and N,N´-bisbenzylidenenaphthalene-1,4-diamines as sirtuin type 2 (SIRT2) inhibitors.
19 Kumpulainen H et al. Evaluation of hydroxyimine as cytochrome P450-selective prodrug structure.
20 Kumpulainen H et al. Convenient microwave-assisted synthesis of 1-chloroethyl phosphates.
21 Kumpulainen H et al. Convenient microwave-assisted synthesis of 1-chloroethyl phosphates.
22 Lapinjoki SP. Marketing authorization of biopharmaceuticals - Critical aspects related to quality and production.
23 Lapinjoki SP, Mikhailopulo IA. Biocatalytic synthesis of pharmaceutically important nucleosides.
24 Mannila A et al. Cerebrospinal fluid distribution of ketoprofen after intravenous administration in young children.
25 Mannila J et al. Precipitation complexation method produces cannabidiol/beta-cyclodextrin inclusion complex suitable for sublingual administration of cannabidiol .
26 Mannila J et al. Sublingual administration of Delta9 -tetrahydrocannabinol/ß-cyclodextrin complex increases the bioavailability of Delta9 -tetrahydrocannabinol in rabbits.
27 Matero S et al. Chemical space of orally active compounds.
28 Matilainen L et al. In vitro evaluation of the effect of cyclodextrin complexation on pulmonary deposition of a peptide, cyclosporin A.
29 Mäki R et al. Controlled release of saccharides from matrix tablets.
30 Mönkkönen H et al. A new endogenous ATP analog (ApppI) inhibits the mitochondrial adenine nucleotide translocase (ANT) and is responsible for the apoptosis induced by nitrogen-containing bisphosphonates.
31 Palmgrén J. Development of Analytical Methods for the Characterization of Absorption Cell Models.
32 Palmgrén JJ et al. Drug adsorption to plastic containers and retention of drugs in cultured cells under in vitro conditions.
33 Parkkari T. Synthesis of Novel Cannabinoid CBI Receptor Ligands.
34 Parkkari T et al. Alpha-methylated derivatives of 2-arachidonoyl glycerol: synthesis, CB1 receptor activity, and enzymatic stability.
35 Parkkari T et al. Synthesis and CB1receptor activities of dimethylheptyl derivatives of 2-arachidonoyl glycerol (2-AG) and 2-arachidonyl glyceryl ether (2-AGE).
36 Parkkari T et al. Synthesis, cannabinoid receptor activity, and enzymatic stability of reversed amide derivatives of arachidonoyl ethanolamide.
37 Poso A, Honkakoski P. Ligand recognition by drug-activated nuclear receptors PXR and CAR: structural, site-directed mutagenesis and molecular modeling studies.
38 Pärssinen O et al. Influence of tamsulosin on the iris and its implications for cataract surgery.
39 Raitio KH et al. Synthesis and in vitro evaluation of novel 2-oxo-1,2-dihydroquinoline CB2 receptor inverse agonists.
40 Raitio KH et al. Synthesis and SAR studies of 2-oxoquinoline derivatives as CB2 receptor inverse agonists.
41 Rautio J et al. In vitro P-glycoprotein inhibition assays for assessment of clinical drug interaction potential of new drug candidates: a recommendation for probe substrates .
42 Roivainen J et al. 9-(1,3-anhydro-beta-D-psicofuranosyl)-adenine.
43 Rönkkö T et al. BRUTUS: Optimization of a grid-based similarity function for rigid-body molecular superposition. II. Description and characterization.
44 Saario SM. Enzymatic Hydrolysis of the Endocannabinoid 2-Arachidonoylglycerol. Characterization and Inhibition in Rat Brain Membranes and Homogenates .
45 Saario SM et al. URB754 has no effect on the hydrolysis or signaling capacity of 2-AG in the rat brain.
46 Saario SM et al. Fatty acid amide hydrolase inhibitors from virtual screening of the endocannabinoid system.
47 Salo OMH. Molecular Modeling of the Endogenous Cannabinoid System. Usability of Modeling Results in Drug Design.
48 Salo OMH et al. 3D-QSAR studies on cannabinoid CB1 receptor agonists: G-protein activation as biological data.
49 Schwab US et al. Effects of hempseed and flaxseed oils on the profile of serum lipids, serum total and lipoprotein lipid concentrations and haemostatic factors.
50 Sivets GG et al. Synthesis of C2´-beta-fluoro-substituted adenine nucleosides via pivaloyl derivatives of adenosine and 3´-deoxyadenosine.
51 Sloan KB et al. Design for optimized topical delivery: prodrugs and a paradigm change .
52 Tervo AJ et al. Discovering inhibitors of human sirtuin type 2: novel structural scaffolds.
53 Toropainen T et al. Preparation of budesonide/gamma-cyclodextrin complexes in supercritical fluids with a novel SEDS method.
54 Tuomainen MH et al. Multivariate analysis of protein profiles of metal hyperaccumulator Thlaspi caerulescens accessions.
55 Venäläinen JI et al. Binding kinetics and duration of in vivo action of novel prolyl oligopeptidase inhibitors.

Farmaseuttisen kemian laitos Department of Pharmaceutical Chemistry
Julkaisutietokanta 15.4.2008 Publications Data Base 15.4.2008