Bioteknologian ja molekulaarisen lääketieteen laitos
Department of Biotechnology and Molecular Medicine

Julkaisut 2004
Publications 2004

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1 Aburawi E et al. Acute respiratory viral infections aggravate arterial endothelial dysfunction in children with type 1 diabetes.
2 Ahola T et al. Thiol metabolism in preterm infants during the first week of life.
3 Airenne KJ et al. Baculovirus-mediated gene transfer: An evolving new concept.
4 Banning A et al. Inhibition of basal and interleukin-1-induced VCAM-1 expression by phospholipid hydroperoxide glutathione peroxidase and 15-lipoxygenase in rabbit aortic smooth muscle cells.
5 Dickinson DA et al. Human glutamate cysteine ligase gene regulation through the electrophile response element.
6 Echeverria V et al. Rat transgenic models with a phenotype of intracellular Abeta accumulation in hippocampus and cortex.
7 Echeverria V et al. Altered mitogen-activated protein kinase signaling, tau hyperphosphorylation and mild spatial learning dysfunction in transgenic rats expressing the beta-amyloid peptide intracellularly in hippocampal and cortical neurons.
8 Grigorenko NA et al. A new synthesis of alfa-methylspermidine.
9 Gruchala M et al. Gene transfer into rabbit arteries with adeno-associated virus and adenovirus vectors.
10 Gruchala M et al. Gene therapy for cardiovascular diseases.
11 Heikkinen S. Glucose Metabolism in Heterozygous Hexokinase II Knock-out Mice.
12 Hytönen VP et al. Efficient production of active chicken avidin using a bacterial signal peptide in Escherichia coli.
13 Hytönen VP et al. Chicken avidin-related protein 4/5 shows superior thermal stability when compared with aviding while retaining high affinity to biotin.
14 Immonen A et al. AdvHSV-tk gene therapy with intravenous ganciclovir improves survival in human malignant glioma: a randomised, controlled stydy.
15 Jänne J et al. Genetic approaches to the cellular functions of polyamines in mammals.
16 Kaasinen SK. Putrescine Accumulation in Mouse Central Nervous System. Neuroprotection at the Expense of Learning Deficiency.
17 Kaasinen SK et al. Spermidine/spermine N1-acetyltransferase overexpression in mice induces hypoactivity and spatial learning impairment.
18 Kankkonen H. Gene Therapy in the Treatment of Familial Hypercholesterolemia. Evaluation and Development of Viral Vectors and Gene Trasfer Techniques.
19 Kankkonen HM et al. Feline immunodeficiency virus and retrovirus-mediated adventitial ex vivo gene transfer to rabbit carotid artery using autologous vasvular smooth muscle cells.
20 Kankkonen HM et al. Long-term lowering of plasma cholesterol levels in LDL-receptor-deficient WHHL rabbits by gene therapy.
21 Karisola P et al. Construction of hevein (Hev b 6.02) with reduced allergenicity for immunotherapy of latex allergy by comutation of six amino acid residues on the conformational IgE epitopes.
22 Ketola A et al. Osteosarcoma and chondrosarcoma as targets for virus vectors and herpes simplex virus thymidine kinase/gangciclovir gene therapy.
23 Kholová I, Kautzner J. Morphology of atrial myocardial extensions into human caval veins.
24 Khurana T et al. Angiogenesis-dependent and independent phases of intimal hyperplasia.
25 Koskinen K et al. Granulocyte transmigration through the endothelium is regulated by the oxidase activity of vascular adhesion protein-1 (VAP-1).
26 Laukkanen-Jalkanen J. Gene Therapy and Atherosclerosis. Experimental Studies with Secreted Macophage Scavenger Receptor and Platelet Activating Factor Acetylhydrolase.
27 Laurema A et al. Fetal membranes act as a barrier for adenoviruses: gene transfer into exocoelomic cavity of rat features does not affect cells in the fetus.
28 Leppänen O et al. Oral imatinib mesylate (STI571/gleevec) improves the efficacy of local intravascular vascular endothelial growth factor-C gene transfer in reducing neointimal growth in hypercholesterolemic rabbits.
29 Mauriala T et al. Determination of long-chain fatty acid acyl-coenzyme A compounds using liquid chromatography-electrospray ionization tandem mass spectrometry.
30 Mähönen AJ et al. Optimized self-excising Cre-expression cassette for mammalian cells.
31 Määttä A-M et al. Non-small cell lung cancer as a target disease for herpes simplex type 1 thymidine kinase - ganciclovir gene therapy.
32 Nordlund HR et al. Construction of a dual chain pseudotetrameric chicken avidin by combining two circularly permuted avidins.
33 Pellinen R et al. Cancer cells as targets for lentivirus-mediated gene transfer and gene therapy.
34 Petrova TV et al. Defective valves and abnormal mural cell recruitment underline lymphatic vascular failure in lymphedema distichiasis.
35 Pirinen E et al. Analysis of the human hexokinase II promoter in vivo: lack of insulin response within 4.0 kb.
36 Porat RM et al. Specific induction tie1 promoter by disturbed flow in atherosclerosis-prone vascular niches and flow-obstructing pathologies.
37 Pulkkanen KJ et al. Cancer gene therapy - current status in the clinics.
38 Rissanen TT et al. Gene transfer for therapeutic vascular growth in myocardial and peripheral ischemia.
39 Rutanen J et al. Adenoviral catheter-mediated intramyocardial gene transfer using the mature form of vascular endothelial growth factor-D induces transmural angiogenesis in porcine heart.
40 Rutanen J et al. Transmyocardial angiogenic effects after intramyocardial adenoviral catheter-mediated VEGF-A and VEGF-D gene transfer in the porcine heart.
41 Räty JK et al. Enhanced gene delivery by avidin-displaying baculovirus.
42 Saaristo A et al. Vascular endothelial growth factor-C gene therapy restores lymphatic flow across incision wounds.
43 Tuhkanen H et al. Genetic alterations in the peritumoral stromal cells of malignant and borderline epithelial ovarian tumors as indicated by allelic imbalance on chromosome 3p.
44 Tuomisto T. Gene Expression in Atherosclerosis and Skeletal Muscle Ischemia. A DNA Array Study.
45 Tuomisto TT et al. HIF-VEGF-VEGFR-2, TNF-alfa and IGF pathways are upregulated in critical human skeletal muscle ischemia as studied with DNA array.
46 Turunen P et al. Adenovirus-mediated gene transfer of Lp-PLA2 reduces LDL degradation and foam cell formation in vitro.
47 Valonen PK et al. Water diffusion in a rat glioma during ganciclovir-thymidine kinase gene therapy-induced programmed cell death in vivo: Correlation with cell density.
48 Vercauteren FGG et al. Early dysregulation of hippocampal proteins in transgenic rats with Alzheimer's disease-linked mutations in amyloid precursor protein and presenilin 1.
49 Walkowiak J, Herzig K-H. The authors' reply [to Vegetarian diet and exocrine pancreatic function using fecal tests].
50 Walkowiak J et al. Giardiasis aggravates malabsorption in cystic fibrosis.
51 Walkowiak J et al. Faecal elastase-1 test is superior to faecal lipase test in the assessment of exocrine pancreatic function in cystic fibrosis.
52 Walkowiak J et al. Serum lipase after secretin stimulation detects mild pancreatic involvement in cystic fibrosis.
53 Walkowiak J et al. Vegetarian diet alters the assessment of exocrine pancreatic function with the use of fecal tests.
54 Ylä-Herttuala S. Therapeutic angiogenesis.
55 Ylä-Herttuala S. Viral vs. non-viral vectors for myocardial angiogenesis.
56 Ylä-Herttuala S, Dzau VJ. Introduction.
57 Ylä-Herttuala S et al. Gene therapy for ischemic cardiovascular diseases: some lessons learned from the first clinical trials.

Bioteknologian ja molekulaarisen lääketieteen laitos Department of Biotechnology and Molecular Medicine
Julkaisutietokanta 15.4.2008 Publications Data Base 15.4.2008