Farmaseuttisen kemian laitos
Department of Pharmaceutical Chemistry

Julkaisut 2001
Publications 2001

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1 Antopolsky M, Azhayev A. Synthesis of peptide-oligonucleotide phosphorothioate conjugates by convergent or stepwise solid-phase strategies.
2 Antopolsky M et al. Towards a general method for the stepwise solid-phase synthesis of peptide-oligonucleotide conjugates.
3 Azhayev AV, Antopolsky ML. Amide group assisted 3'-dephosphorylation of oligonucleotides synthesized on universal A-supports.
4 Damen EWP et al. Synthesis of novel paclitaxel prodrugs designed for bioreductive activation in hypoxic tumour tissue.
5 Frith JC et al. The molecular mechanism of action of the antiresorptive and antiinflammatory drug clodronate.
6 Gynther J. Farmasian koulutustavoitteet kasvavat - riittävätkö resurssit?
7 Gynther J. Proviisoreista toksikologian asiantuntijoita.
8 Jarho P et al. The effect of cyclodextrin and pH on cyclodextrincatalyzed deacetylation of spironolactone.
9 Laine K et al. Kannabinoidit - tulevaisuuden lääkeaineita?
10 Laine K et al. Effects of topical anandamide-transport inhibitors, AM404 and olvanil, on intraocular pressure in normotensive rabbits.
11 Lapinjoki S. Miten, milloin ja miksi lääkkeet vanhenevat.
12 Leppänen J et al. Synthesis and in-vitro/in-vivo evaluation of orally administered entacapone prodrugs.
13 Leppänen J et al. Structural studies of acyl esters of entacapone.
14 Másson M et al. Methodology for mesuring the stability of drugs in cyclodextrin solutions and estimating stability in pharmaceutical formulations.
15 Mönkkönen H et al. The cellular uptake and metabolism of clodronate in RAW 264 macrophages.
16 Niemi R. Bisfosfonaattien ominaisuuksien parantaminen aihiolääketeknologialla.
17 Poso A et al. A comparative molecular field analysis of cytochrome P450 2A5 and 2A6 inhibitors.
18 Raiman J et al. Effects of calcium and lipophilicity on transport of clodronate and its esters through Caco-2 cells.
19 Rautiainen J et al. Two new variants of the lipocalin allergen Bos d 2.
20 Savinainen JR et al. Despite substantial degradation, 2-arachidonoylglycerol is a potent full efficacy agonist mediating CB1 receptor-dependent G-protein activation in rat cerebellar membranes.
21 Suihko E et al. Complexation with tolbutamide modifies the physicochemical and tableting properties of hydroxypropyl-beta-cyclodextrin.
22 Tarvainen M et al. Predicting plasticization efficiency from three-dimensional molecular structure of a polymer plasticizer.
23 Tiihonen J et al. Free L-tryptophan plasma levels in antisocial violent offenders.
24 Tupala E et al. Dopamine D2/D3-receptor and transporter densities in nucleus accumbens and amygdala of type 1 and 2 alcoholics.
25 Turhanen PA et al. Bisphosphonate prodrugs. Synthesis and identification of (1-hydroxyethylidene)-1,1-bisphosphonic acid tetraesters by mass spectrometry, NMR spectroscopy and X-ray crystallography.

Farmaseuttisen kemian laitos Department of Pharmaceutical Chemistry
Julkaisutietokanta 15.4.2008 Publications Data Base 15.4.2008