A.I. Virtanen -instituutti
A.I. Virtanen Institute for Molecular Sciences

Julkaisut 2001
Publications 2001

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1 Barbelivien A et al. Inhibition of MAO-A activity enhances behavioural activity of rats assessed using water maze and open area tasks.
2 Barbelivien A et al. Metabolic alterations in the prefrontal and cingulate cortices are related to behavioral deficits in a rodent model of attention-deficit hyperactivity disorder.
3 Bras APM et al. Spermidine/spermine N1-acetyltransferase catalyzes amantadine acetylation.
4 Bräsen JH et al. Angiogenesis, vascular endothelial growth factor and platelet-derived growth factor-BB expression, iron deposition, and oxidation-specific epitopes in stented human coronary arteries.
5 Castrén E, Castrén M. Hermosolusiirrot neurologisten tautien hoidossa.
6 Castrén M et al. Subcellular localization of fragile X mental retardation protein with I304N mutation in the RNA-binding domain in cultured hippocampal neurons.
7 Chen Y et al. Astrocytes protect neurons from nitric oxide toxicity by a glutathione-dependent mechanism.
8 Enholm B et al. Adenoviral expression of vascular endothelial growth factor-C induces lymphangiogenesis in the skin.
9 Golay X et al. Measurement of tissue oxygen extraction ratios from venous blood T(2): increased precision and validation of principle.
10 Greaves DR et al. Linked chromosome 16q13 chemokines, macrophage-derived chemokine, fractalkine, and thymus- and activation-regulated chemokine, are expressed in human atherosclerotic lesions.
11 Gröhn OHJ, Kauppinen RA. Assessment of brain tissue viability in acute ischemic stroke by BOLD NMR.
12 Haapasalo A et al. Truncated trkB.T1 is dominant negative inhibitor of trkB.TK+-mediated cell survival.
13 Halonen T et al. Effect of lamotrigine treatment on status epilepticus-induced neuronal damage and memory impairment in rat.
14 Halonen T et al. Chronic elevation of brain GABA levels beginning two days after status epilepticus does not prevent epileptogenesis in rats.
15 Heikkilä A et al. Angiographically guided utero-placental gene transfer in rabbits with adenoviruses, plasmid/liposomes and plasmid/polyethyleneimine complexes.
16 Heydeck D et al. Oxidation of LDL by rabbit and human 15-lipoxygenase: prevalence of nonenzymatic reactions.
17 Hiltunen TP et al. Rabbit atherosclerotic lesions express scavenger receptor AIII mRNA, a naturally occurring splice variant that encodes a non-functional, dominant negative form of the macrophage scavenger receptor.
18 Iljin K et al. VEGFR3 gene structure, regulatory region, and sequence polymorphisms.
19 Jolkkonen E. Central Nucleus of the Rat Amygdala: Cytoarchitectural, chemoarchitectural, and connectional characteristics.
20 Jolkkonen E et al. Projections from the amygdalo-piriform transition area to the amygdaloid coplex: A PHA-L study in rat.
21 Jolkkonen E et al. Interconnectivity between the amygdaloid complex and the amygdalostriatal transition area: a PHA-L study in rat.
22 Jolkkonen J et al., ed. 11th Nordic Meeting on Cerebrovascular Diseases and 2nd Biennial Symposium on Ischaemic Stroke.
23 Jutila L et al. Neurobiology of epileptogenesis in the temporal lobe.
24 Jutila L et al. MR volumetry of the entorhinal, perirhinal, and temporopolar cortices in drug-refractory temporal lobe epilepsy.
25 Karkkainen MJ et al. A model for gene therapy of human hereditary lymphedema.
26 Karpanen T et al. Vascular endothelial growth factor C promotes tumor lymphangiogenesis and intralymphatic tumor growth.
27 Kavec M et al. Use of spin echo T2 BOLD in assessment of cerebral misery perfusion at 1.5 T.
28 Kettunen MI et al. Cerebral T1rho relaxation time increases immediately upon global ischemia in the rat independently of blood glucose and anoxic depolarization.
29 Koistinaho M. Beta Amyloid Precursor Protein-Induced Changes in Behavior and Ischemic Vulnerability - Roles of Apolipoprotein E and Inflammation.
30 Koistinaho M et al. Specific spatial learning deficits become severe with age in beta-amyloid precursor protein transgenic mice that harbor diffuse beta-amyloid deposits but do not form plaques.
31 Korhonen V-P et al. Spermine deficiency resulting from targeted disruption of the spermine synthase gene in embryonic stem cells leads to enhanced sensitivity to antiproliferative drugs.
32 Koskinen T. The Role of 5-HT2 Receptors in the Modulation of Premature Responding Type of Impulsivity in Rats. Interactions with Dopaminergic and Noradrenergic Systems.
33 Koskinen T, Sirviö J. Studies on the involvement of the dopaminergic system in the 5-HT2 agonist (DOI)-induced premature responding in a five-choice serial reaction time task.
34 Kubová H et al. Status epilepticus causes necrotic damage in the mediodorsal nucleus of the thalamus in immature rats.
35 Kukkonen JP et al. Modelling of promiscuous receptor-Gi/Gs-protein coupling and effector response.
36 Kurkinen K et al. Isoform-specific membrane translocation of protein kinase C after ischemic preconditioning.
37 Kurkinen K et al. Preconditioning with spreading depression activates specifically protein kinase Cdelta.
38 Laukkanen MO. Cloning, Expression, and Therapeutical Effects of Rabbit Extracellular Superoxide Dismutase.
39 Laukkanen MO et al. EC-SOD gene therapy reduces paracetamol-induced liver damage in mice.
40 Laukkanen MO et al. Gene transfer of extracellular superoxide dismutase to atherosclerotic mice.
41 Leppänen PM et al. Optimized in situ PCR method for the detection of gene transfer vector in histological sections.
42 Lindén A-M et al. Increased expression of neuronal Src and tyrosine phosphorylation of NMDA receptors in rat brain after systemic treatment with MK-801.
43 Lindén A-M et al. Uncompetitive antagonists of the N-methyl-D-aspartate (NMDA) receptors alter the mRNA expression of proteins associated with the NMDA receptor complex.
44 Loimas S. Herpes Simplex Virus Type I Thymidine Kinase - Green Fluorescent Protein Fusion Gene as a Tool in Cancer Gene Therapy Research.
45 Loimas S et al. Human prostate carcinoma cells as targets for herpes simplex virus thymidine kinase-mediated suicide gene therapy.
46 Lukasiuk K et al. Time course and mechanisms of amygdaloid damage after kainate-induced status epilepticus in rat.
47 Marvanová M et al. The neuroprotective agent memantine induces brain-derived neurotrophic factor and trkB receptor expression in rat brain.
48 Mäkelä HI et al. Proton exchange as a relaxation mechanism for T1 in the rotating frame in native and immobilized protein solutions.
49 Mäkinen T et al. Inhibition of lymphangiogenesis with resulting lymphedema in transgenic mice expressing soluble VEGF receptor-3.
50 Nieminen MT et al. T2 Relaxation reveals spatial collagen architecture in articular cartilage: a comparative quantitative MRI and polarized light microscopic study.
51 Nissinen J et al. Is mossy fiber sprouting present at the time of the first spontaneous seizures in rat experimental temporal lobe epilepsy?
52 Närvänen O et al. Evaluation and characterization of EIA measuring autoantibodies against oxidized LDL.
53 Närvänen O et al. Technical and clinical aspects about autoantibody assays for oxidized low density lipoprotein.
54 Pietilä M. Activation of Polyamine Catabolism in Transgenic Mice.
55 Pietilä M et al. Relation of skin polyamines to the hairless phenotype in transgenic mice overexpressing spermidine/spermine N1-acetyltransferase.
56 Pikkarainen M. The Rat Parahippocampal Region . Chemoarchitectonics and Afferent Connections from the Amygdala with Special Emphasis on the Entorhinal Cortex.
57 Pikkarainen M, Pitkanen A. Projections from the lateral, basal and accessory basal nuclei of the amygdala to the perirhinal and postrhinal cortices in rat.
58 Pirttilä T-RM et al. Ex vivo MR microimaging of neuronal damage after kainate-induced status epilepticus in rat: correlation with quantitative histology.
59 Pulkkanen K. Gene Therapy for Human Renal Cell Carcinoma in an Orthotopic Nude Mouse Model.
60 Pulkkanen KJ et al. HSV-tk gene therapy for human renal cell carcinoma in nude mice.
61 Puurunen K et al. An alfa2-adrenergic antagonist, atipamezole, facilitates behavioral recovery after focal cerebral ischemia in rats.
62 Puurunen K et al. Selegiline combined with enriched-environment housing attenuates spatial learning deficits following focal cerebral ischemia in rats.
63 Puurunen K et al. Enriched-environment housing increases neuronal Fos-staining in the dentate gyrus after a water maze spatial learning task.
64 Rissanen TT et al. Gene therapy for therapeutic angiogenesis in critically inschaemic lower limb - on the way to the clinic.
65 Rutanen J et al. Clinical applications of vascular gene therapy.
66 Saarelainen T. Functions of BDNF in Adult Brain - Studies Using Transgenic Mice Overexpressing Truncated trkB Receptor in Brain.
67 Saarelainen T et al. trkB-receptor activation contributes to the kainate-induced increase in BDNF mRNA synthesis.
68 Salmenperä T et al. Hippocampal and amygdaloid damage in partial epilepsy A cross-sectional MRI study of 241 patients.
69 Sentman M-L et al. Extracellular superoxide dismutase deficiency and atherosclerosis in mice.
70 Suppola S et al. Concurrent overexpression of ornithine decarboxylase and spermidine/spermine N1-acetyltransferase further accelerates the catabolism of hepatic polyamines in transgenic mice.
71 Sutula TP, Pitkänen A. More evidence for seizure-induced neuron loss: is hippocampal sclerosis both cause and effect of epilepsy?
72 Tikka T. Neuroprotective Effects of Tetracycline Derivatives in Primary Cell Culture Models of Excitotoxicity and Inflammation.
73 Tikka T et al. Minocycline, a tetracycline derivative, is neuroprotective against excitotoxicity by inhibiting activation and proliferation of microglia.
74 Tikka T et al. Tetracycline derivatives and ceftriaxone, a cephalosporin antibiotic, protect neurons against apoptosis induced by ionizing radiation.
75 Tikka TM, Koistinaho JE. Minocycline provides neuroprotection against N-methyl-D-aspartate neurotoxicity by inhibiting microglia.
76 Vartiainen N et al. Piroxicam and NS-398 rescue neurones from hypoxia/reoxygenation damage by a mechanism independent of cyclo-oxygenase inhibition.
77 Wahlfors J et al. Green fluorescent protein (GFP) fusion constructs in gene therapy research.
78 Ylä-Herttuala S. Geeniterapia.
79 Ylä-Herttuala S. Gene therapy for coronary heart disease.
80 Zhou J et al. Inverse T2 contrast at 1.5 tesla between gray matter and white matter in the occipital lobe of normal adult human brain.

A.I. Virtanen -instituutti A.I. Virtanen Institute for Molecular Sciences
Julkaisutietokanta 15.4.2008 Publications Data Base 15.4.2008