Farmaseuttisen kemian laitos
Department of Pharmaceutical Chemistry

Julkaisut 1999
Publications 1999

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1 Ahlmark M et al. Bisphosphonate prodrugs: synthesis and in vitro evaluation of novel clodronic acid dianhydrides as bioreversible prodrugs of clodronate.
2 Antopolsky M, Azhayev A. Stepwise solid-phase synthesis of peptide-oligonucleotide conjugates on new solid supports.
3 Antopolsky M et al. Peptide-oligonucleotide phosphorothioate conjugates with membrane translocation and nuclear localization properties.
4 Antopolsky M et al. General method to synthesize disulfide cross-linked peptide-oligonucleotide phosphorothioate conjugates.
5 Auriola S et al. Analysis of adenine nucleotide containing metabolite of clodronate using ion pair HPLC-ESI-MS.
6 Azhayev A. Universal solid supports for oligonucleotide synthesis.
7 Azhayev AV. A new universal solid support for oligonucleotide synthesis.
8 Benford HL et al. Farnesol and geranylgeraniol prevent activation of caspases by aminobisphosphonates: biochemical evidence for two distinct pharmacological classes of bisphosphonate drugs.
9 Callaway JC. Phytochemistry and neuropharmacology of ayahuasca.
10 Callaway JC et al. Pharmacokinetics of hoasca alkaloids in healthy humans.
11 Fredholt K et al. Alfa-chymotrypsin-catalyzed degradation of desmopressin (dDAVP): influence of pH, concentration and various cyclodextrins.
12 Guzaev A et al., inventor. Chemical phosphorylation of oligonucleotides and reactants used therefor.
13 Gynther J, Järvinen T. Kuopion yliopistossa kehitetään uusia lääkeaineita.
14 Haataja S et al. Determination of the cell adhesion specificity of Streptococcus suis with the complete set of monodeoxy analogues of globotriose.
15 Hakala K et al. Mass spectrometric (HPLC/ESI-MS/MS) quantification of pyrimido[1,2-a]purin-10(3H)-one, a guanine adduct formed by reaction of malondialdehyde with DNA.
16 Kovalainen JT et al. Synthesis and in vitro pharmacology of a series of new chiral histamine H3-receptor ligands: 2-(R and S)-amino-3-(1H-imidazol-4(5)-yl) propyl ether derivatives.
17 Kovalainen JT et al. 1H NMR study on putative intramolecular hydrogen bonding for histamine H3-receptor agonists.
18 Kovalainen JT et al. 4-(3-(4-iodophenylmethoxy)propyl)-1H-imidazolium hydrogen maleate (iodoproxyfan hydrogen maleate).
19 Loftssona T, Järvinen T. Cyclodextrins in ophthalmic drug delivery.
20 Makkonen N et al. Contrasting effects of alendronate and clodronate on RAW 264 macrophages: the role of a bisphosphonate metabolite.
21 Mönkkönen J et al. Effects of bisphosphonates on the inflammatory processes of activated macrophages.
22 Niemi R et al. Bisphosphonate prodrugs: synthesis and in vitro evaluation of novel acyloxyalkyl esters of clodronic acid.
23 Pate DW. Anandamide Structure-Activity Relationships and Mechanisms of Action on Intraocular Pressure in the Normotensive Rabbit Model.
24 Pate DW et al., inventor. Anandamide analog compositions and method of treating intraocular hypertension using same.
25 Rautio J et al. Synthesis and in vitro evaluation of aminoacyloxyalkyl esters of 2-(6-methoxy-2-naphthyl) propionic acid as novel naproxen prodrugs for dermal drug delivery.
26 Rogers MJ et al. Molecular mechanisms of action of bisphosphonates.
27 Savolainen J et al. Coadministration of a water-soluble polymer increases the usefulness of cyclodextrins in solid oral dosage forms.
28 Sznitowska M et al. Miotic effect and irritation potential of pilocarpine prodrug incorporated into a submicron emulsion vehicle.
29 Tarvainen T et al. Drug release from a porous ion-exchange membrane in vitro.
30 Tikkanen K, Finne J, inventors. Streptococcus suis adhesin protein and method for producing it.
31 Toroskainen C, Auriola S. Antibioottiset peptidit.
32 Vähätalo H et al. High-performance liquid chromatography-mass spectrometry of an osteocalcin derivative.
33 Ylitalo P et al. Comparison of pharmacokinetics of clodronate after single and repeated doses.

Farmaseuttisen kemian laitos Department of Pharmaceutical Chemistry
Julkaisutietokanta 15.4.2008 Publications Data Base 15.4.2008