A.I. Virtanen -instituutti
A.I. Virtanen Institute for Molecular Sciences

Julkaisut 1998
Publications 1998

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1 Ahotupa M et al. Baseline diene conjugation in LDL lipids as a direct measure of in vivo LDL oxidation.
2 Alhonen L. Eläinbioteknologia tuottaa malleja tutkijan työkaluiksi.
3 Alhonen L et al. Correlation of polyamine and growth responses to N1, N11-diethylnorspermine in primary fetal fibroblasts derived from transgenic mice overexpressing spermidine/spermine N1-acetyltransferase.
4 Berliner J, Ylä-Herttuala S. The atherosclerotic lesion: a dynamic landscape.
5 Björklund M et al. Alpha2C-adrenoceptor-overexpressing mice are impaired in executing nonspatial and spatial escape strategies.
6 Castro FO, Jänne J, eds. Mammary Gland Transgenesis. Therapeutic Protein Production.
7 Castrén E et al. Regulation of brain-derived neurotrophic factor mRNA levels in hippocampus by neuronal activity.
8 Castrén E et al. Mitä uutta neurofarmakologiasta?
9 Drago J et al. Targeted expression of a toxin gene to D1 dopamine receptor neurons by Cre-mediated site-specific recombination.
10 European Carotid Surgery Trialists´ Collaborative Group. Randomised trial of endarterectomy for recently symptomatic carotid stenosis: final results of the MRC European Carotid Surgery Trial (ECST).
11 Gröhn OHJ et al. Noninvasive detection of cerebral hypoperfusion and reversible ischemia from reductions in the magnetic resonance imaging relaxation time, T2.
12 Haapalinna A et al. Facilitation of cognitive functions by a specific alpha2-adrenoceptor antagonist, atipamezole.
13 Hakumäki JM et al. Quantitative 1H nuclear magnetic resonance diffusion spectroscopy of BT4C rat glioma during thymidine kinase-mediated gene therapy in vivo: Identification of apoptotic response.
14 Heikkinen A-M et al. Postmenopausal hormone replacement therapy and autoantibodies against oxidized LDL.
15 Hendolin M. Generation of Transgenic Cattle . The Fate of Foreign DNA in Microinjected Bovine in Vitro Produced Embryos.
16 Hiltunen M et al. Butyrylcholinesterase K variant and apolipoprotein E4 genes do not act in synergy in Finnish late-onset Alzheimer´s disease patients.
17 Hiltunen MO et al. Geeniterapia verisuonitautien hoidossa.
18 Hiltunen MO, Ylä-Herttuala S. Kani eläinmallina ateroskleroosin geeniterapiatutkimuksissa.
19 Hiltunen TP et al. Expression of LDL receptor, VLDL receptor, LDL receptor-related protein, and scavenger receptor in rabbit atherosclerotic lesions. Marked induction of scavenger receptor and VLDL receptor expression during lesion development.
20 Hiltunen TP, Ylä-Herttuala S. Expression of lipoprotein receptors in atherosclerotic lesions.
21 Hyttinen J-M et al. High-level expression of bovine beta-lactoglobulin gene in transgenic mice.
22 Häkkinen T, Ylä-Herttuala S. Artifact occurring during combined in situ hybridization and immunocytochemistry analysis because of positive chemography.
23 Hökfelt T et al. Neuropeptide Y: some viewpoints on a multifaceted peptide in the normal and diseased nervous system.
24 Imai S et al. Osteoblast recruitment and bone formation enhanced by cell matrix-associated heparin-binding growth-associated molecule (HB-GAM).
25 Insausti R et al. MR volumetric analysis of the human entorhinal, perirhinal, and temporopolar cortices.
26 Jolkkonen E, Pitkänen A. Intrinsic connections of the rat amygdaloid complex: projections originating in the central nucleus.
27 Juottonen K et al. Volumes of the entorhinal and perirhinal cortices in Alzheimer`s disease.
28 Juottonen K et al. Major decrease in the volume of the entorhinal cortex in patients with Alzheimer`s disease carrying the apolipoprotein E epsilon4 allele.
29 Juvonen PO et al. Lipid peroxidation products and antioxidant capacity in portal venous and systemic arterial plasma during gradual intestinal ischemia and reperfusion in pigs.
30 Jänne J. Transgenic bioreactors.
31 Jänne J, Alhonen L. Transgenic livestock as bioreactors.
32 Jänne J et al. Transgenic dairy cattle.
33 Jänne J et al. Transgenic bioreactors.
34 Kaartinen J et al. Automated quantification of human brain metabolites by artificial neural network analysis from in vivo single-voxel 1H NMR spectra.
35 Kauppinen RA, Williams SR. Use of NMR spectroscopy in monitoring cerebral pH and metabolism during systemic and focal acid-base disturbances.
36 Korhonen A-L et al. Lyhytkestoinen painonhallintakurssi lihavien nuorten hoidossa.
37 Kraszpulski M et al. Pitfalls in the quantitative estimation of beetta-amyloid immunoreactivity in human brain tissue.
38 Kumlin T et al. Epidermal ornithine decarboxylase and polyamines in mice exposed to 50 Hz magnetic fields and UV radiation.
39 Kumlin T et al. Effects of 50 Hz magnetic fields on UV-induced skin tumourigenesis in ODC-transgenic and non-transgenic mice.
40 Kälviäinen R et al. Recurrent seizures may cause hippocampal damage in temporal lobe epilepsy.
41 Laakso MP et al. MRI of the hippocampus in Alzheimer`s disease: sensitivity, specificity, and analysis of the incorrectly classified subjects.
42 Laitinen M et al. Adenovirus-mediated gene transfer to lower limb artery of patients with chronic critical leg ischemia.
43 Laitinen M, Ylä-Herttuala S. Adventitial gene transfer to arterial wall.
44 Laitinen M, Ylä-Herttuala S. Vascular gene transfer for the treatment of restenosis and atherosclerosis.
45 Laitinen M, Ylä-Herttuala S. Adventitial gene transfer to rabbit carotid arteries.
46 Lappalainen R et al. Association of sociodemographic factors with barriers reported by patients receiving nutrition counseling as part of cardiac rehabilitation.
47 Lehtovirta M et al. Longitudinal SPECT study in Alzheimer`s disease: relation to apolipoprotein E polymorphism.
48 Leinonen JS et al. The level of autoantibodies against oxidized LDL is not associated with the presence of coronary heart disease or diabetic kidney disease in patients with non-insulin-dependent diabetes mellitus.
49 Leppänen P et al. Characterization of atherosclerotic lesions in apo E3-leiden transgenic mice.
50 Loimas S et al. Herpes simplex virus thymidine kinase-green fluorescent protein fusion gene: new tool for gene transfer studies and gene therapy .
51 Lukkarinen JA et al. Neuroprotective role of ornithine decarboxylase activation in transient focal cerebral ischaemia: a study using ornithine decarboxylase-overexpressing transgenic rats.
52 Luoma H et al. Seven weeks feeding of magnesium and fluoride modifies plasma lipids of hypercholesterolaemic rats in late growth phase.
53 Luoma JS et al. Expression of extracellular SOD and iNOS in macrophages and smooth muscle cells in human and rabbit atherosclerotic lesions: colocalization with epitopes characteristic of oxidized LDL and peroxynitrite-modified proteins.
54 Manninen HI et al. Intravascular ultrasound and magnetic resonance imaging in the assessment of atherosclerotic lesions in rabbit aorta. Correlation to histopathologic findings.
55 Meurman JH et al. Saliva in non-insulin-dependent diabetic patients and control subjects: the role of the autonomic nervous system.
56 Miettinen R et al. Hippocampal damage after injection of kainic acid into the rat entorhinal cortex.
57 Mikkonen M et al. Remodeling of neuronal circuitries in human temporal lobe epilepsy: increased expression of highly polysialylated neural cell adhesion molecule in the hippocampus and the entorhinal cortex.
58 Mäkinen K et al. Azaserine-induced rat pancreas tumor model with transplantable cultured cells.
59 Niittykoski M et al. Systemic administration of atipamezole, a selective antagonist of alpha-2 adrenoceptors, facilitates behavioural activity but does not influence short-term or long-term memory in trimethyltin-intoxicated and control rats.
60 Panula HE et al. Subchondral bone remodeling increases in early experimental osteoarthrosis in young beagle dogs.
61 Penttonen M et al. Gamma frequency oscillation in the hippocampus of the rat: intracellular analysis in vivo.
62 Pirinen RT et al. Expression of hyaluronan in normal and dysplastic bronchial epithelium and in squamous cell carcinoma of the lung.
63 Pirttilä T et al. Longitudinal study of cerebrospinal fluid amyloid proteins and apolipoprotein E in patients with probable Alzheimer`s disease.
64 Pitkänen A. Mantelitumake.
65 Pitkänen A, Amaral DG. Organization of the intrinsic connections of the monkey amygdaloid complex: projections originating in the lateral nucleus.
66 Pitkänen A, Halonen T. Prevention of epilepsy.
67 Pitkänen A et al. Amygdala damage in experimental and human temporal lobe epilepsy.
68 Poptani H et al. Monitoring thymidine kinase and ganciclovir-induced changes in rat malignant glioma in vivo by nuclear magnetic resonance imaging.
69 Puranen J et al. Efficacy of antiplatelet treatment in hypertensive patients with TIA or stroke.
70 Pussinen R, Sirviö J. Minor role for alpha1-adrenoceptors in the facilitation of induction and early maintenance of long-term potentiation in the CA1 field of the hippocampus.
71 Pussinen R et al. Preserved induction of long-term potentiation in the stratum radiatum in the CA1 field of hippocampal slices from transgenic mice overexpressing ornithine decarboxylase and overproducing putrescine.
72 Puumala T et al. Stimulation of alpha-1 adrenergic receptors facilitates spatial learning in rats.
73 Puumala T, Sirviö J. Changes in activities of dopamine and serotonin systems in the frontal cortex underlie poor choice accuracy and impulsivity of rats in an attention task.
74 Puumalainen A-M et al. Beta-galactosidase gene transfer to human malignant glioma in vivo using replication-deficient retroviruses and adenoviruses.
75 Puumalainen A-M et al. Geenihoidon mahdollisuudet ja vaarat.
76 Puumalainen A-M et al. Gene therapy for malignant glioma patients.
77 Reeben M et al. The messenger RNAs for both glial cell line-derived neurotrophic factor receptors, c-ret and GDNFRalpha, are induced in the rat brain in response to kainate-induced excitation.
78 Riekkinen M et al. Tetrahydroaminoacridine improves the recency effect in Alzheimer's disease.
79 Ropponen K et al. Tumor cell-associated hyaluronan as an unfavorable prognostic factor in colorectal cancer.
80 Ruotsalainen S et al. 5-HT1A receptor agonist (8-OH-DPAT) and 5-HT2 receptor agonist (DOI) disrupt the non-cognitive performance of rats in a working memory task.
81 Ruotsalainen S et al. The role of the dorsal raphe-serotonergic system and cholinergic receptors in the modulation of working memory.
82 Salmenperä T et al. Hippocampal damage caused by seizures in temporal lobe epilepsy.
83 Soininen HS, Riekkinen PJ Sr. ApoE and memory in Alzheimer´s disease.
84 Sorvari H et al. Calretinin-immunoreactive terminals make synapses on calbindin D28k-immunoreactive neurons in the lateral nucleus of the human amygdala.
85 Spets-Happonen S et al. Accumulation of strontium and fluoride in approximal dental plaque and changes in plaque microflora after rinsing with chlorhexidine-fluoride-strontium solution.
86 Tapiola T et al. Increased aspartate aminotransferase activity in cerebrospinal fluid and Alzheimer´s disease.
87 Tapiola T et al. CSF tau is related to apolipoprotein E genotype in early Alzheimer's disease.
88 Tenhunen K et al. Monitoring the CNS pathology in aspartylglucosaminuria mice.
89 The Ronald and Nancy Reagan Research Institute of the Alzheimer's ... Consensus report of the working group on: Molecular and biochemical markers of Alzheimer´s disease.
90 Valeyev AY et al. Embryonic rat hippocampal neurons and GABAA receptor subunit-transfected non-neuronal cells release GABA tonically.
91 van Zijl PCM et al. Quantitative assessment of blood flow, blood volume and blood oxygenation effects in functional magnetic resonance imaging.
92 van Zijl PCM et al. Veren virtauksen, veritilavuuden ja veren happiosapaineen vaikutusten kvantifiointi toiminnallisella magneettikuvauksella.
93 Vanhanen M et al. Cognitive function in an elderly population with persistent impaired glucose tolerance.
94 Ylinen A. Antiepileptic efficacy of vigabatrin in people with severe epilepsy and intellectual disability.
95 Ylitalo R et al. Effects of liposome-encapsulated bisphosphonates on acetylated LDL metabolism, lipid accumulation and viability of phagocyting cells.
96 Ylä-Herttuala S. Is oxidized low-density lipoprotein present in vivo?
97 Ylä-Herttuala S. Gene therapy and brain tumors.
98 Yrjänheikki J et al. Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia.

A.I. Virtanen -instituutti A.I. Virtanen Institute for Molecular Sciences
Julkaisutietokanta 15.4.2008 Publications Data Base 15.4.2008